Institutional Repository, Institute of Psychology, Chinese Academy of Sciences
| Characteristics of the beta-globin gene cluster haplotypes of three Han Chinese populations at Beijing, Xi'an, and Kunming as compared with those of other Asian populations. | |
Koji Shimizu; Erika Nagaoka; Yusuke Okada; Yukiko Takeuchi; Shinji Harihara; Keiichi Omoto; Tadashi Imanishi; Wook Kim; Dong-Jik Shin; Luping Hao; Jin F(金锋)
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| 通讯作者邮箱 | shimizuk@naruto-u.ac.jp ; hnckb157@ybb.ne.jp |
| 心理所单位排序 | 8 |
| 摘要 | Haplotype frequencies of the beta-globin gene cluster of Han Chinese at Beijing, Xi'an, and Kunming were estimated, and their mutual genetic relationships were examined and compared to those of Buryats, Khalkhs, Evenkis, Oroqens, Koreans, and Colombian Amerindians. A major 5' subhaplotype (5' to the delta-globin gene), a major 3' subhaplotype (in and 3' to the beta-globin gene), and a major haplotype (combination of 5' and 3' subhaplotypes) are represented as + - - - -, - +, and + - - - - - +, respectively, and found in all three Han Chinese. A rare 5' subhaplotype, - - - - -, which is one of the possible ancestral types, was found only in Han Chinese at Kunming at low frequency (0.013), and a rare 3' subhaplotype, - -, was also observed in all three Han Chinese at low frequencies (0.009-0.014). The present haplotype frequency study suggested that the highest genetic affinity was found between Han Chinese at Beijing and those at Xi'an; the next highest was between Han Chinese at Beijing and Koreans, followed by that between Han Chinese at Beijing and Khalkhs, then that between Han Chinese at Xi'an and those at Kunming or Khalkhs, and finally that between Han Chinese at Beijing and those at Kunming. A genetic boundary between northern and southern Han Chinese was not evident in the present study. |
| 关键词 | b-Globin gene cluster haplotype Han Chinese Asian populations |
| 学科领域 | 生理心理学/生物心理学 ; 心理人类学 |
| 2008 | |
| 语种 | 英语 |
| DOI | 10.1007/s10528-008-9171-9 |
| 发表期刊 | Biochemical Genetics
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| 卷号 | 46期号:9-10页码:566-582. |
| URL | 查看原文 |
| 收录类别 | SCI |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.psych.ac.cn/handle/311026/10026 |
| 专题 | 中国科学院心理研究所回溯数据库(1956-2010) |
| 推荐引用方式 GB/T 7714 | Koji Shimizu,Erika Nagaoka,Yusuke Okada,et al. Characteristics of the beta-globin gene cluster haplotypes of three Han Chinese populations at Beijing, Xi'an, and Kunming as compared with those of other Asian populations.[J]. Biochemical Genetics,2008,46(9-10):566-582.. |
| APA | Koji Shimizu.,Erika Nagaoka.,Yusuke Okada.,Yukiko Takeuchi.,Shinji Harihara.,...&Jin F.(2008).Characteristics of the beta-globin gene cluster haplotypes of three Han Chinese populations at Beijing, Xi'an, and Kunming as compared with those of other Asian populations..Biochemical Genetics,46(9-10),566-582.. |
| MLA | Koji Shimizu,et al."Characteristics of the beta-globin gene cluster haplotypes of three Han Chinese populations at Beijing, Xi'an, and Kunming as compared with those of other Asian populations.".Biochemical Genetics 46.9-10(2008):566-582.. |
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