Characteristics of the beta-globin gene cluster haplotypes of three Han Chinese populations at Beijing, Xi'an, and Kunming as compared with those of other Asian populations.
Koji Shimizu; Erika Nagaoka; Yusuke Okada; Yukiko Takeuchi; Shinji Harihara; Keiichi Omoto; Tadashi Imanishi; Wook Kim; Dong-Jik Shin; Luping Hao; Jin F(金锋)
2008
发表期刊Biochemical Genetics
通讯作者邮箱shimizuk@naruto-u.ac.jp ; hnckb157@ybb.ne.jp
卷号46期号:9-10页码:566-582.
产权排序8
摘要Haplotype frequencies of the beta-globin gene cluster of Han Chinese at Beijing, Xi'an, and Kunming were estimated, and their mutual genetic relationships were examined and compared to those of Buryats, Khalkhs, Evenkis, Oroqens, Koreans, and Colombian Amerindians. A major 5' subhaplotype (5' to the delta-globin gene), a major 3' subhaplotype (in and 3' to the beta-globin gene), and a major haplotype (combination of 5' and 3' subhaplotypes) are represented as + - - - -, - +, and + - - - - - +, respectively, and found in all three Han Chinese. A rare 5' subhaplotype, - - - - -, which is one of the possible ancestral types, was found only in Han Chinese at Kunming at low frequency (0.013), and a rare 3' subhaplotype, - -, was also observed in all three Han Chinese at low frequencies (0.009-0.014). The present haplotype frequency study suggested that the highest genetic affinity was found between Han Chinese at Beijing and those at Xi'an; the next highest was between Han Chinese at Beijing and Koreans, followed by that between Han Chinese at Beijing and Khalkhs, then that between Han Chinese at Xi'an and those at Kunming or Khalkhs, and finally that between Han Chinese at Beijing and those at Kunming. A genetic boundary between northern and southern Han Chinese was not evident in the present study.
关键词b-Globin gene cluster haplotype Han Chinese Asian populations
学科领域生理心理学/生物心理学 ; 心理人类学
DOI10.1007/s10528-008-9171-9
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收录类别SCI
语种英语
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被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/10026
专题中国科学院心理研究所回溯数据库(1956-2010)
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GB/T 7714
Koji Shimizu,Erika Nagaoka,Yusuke Okada,et al. Characteristics of the beta-globin gene cluster haplotypes of three Han Chinese populations at Beijing, Xi'an, and Kunming as compared with those of other Asian populations.[J]. Biochemical Genetics,2008,46(9-10):566-582..
APA Koji Shimizu.,Erika Nagaoka.,Yusuke Okada.,Yukiko Takeuchi.,Shinji Harihara.,...&Jin F.(2008).Characteristics of the beta-globin gene cluster haplotypes of three Han Chinese populations at Beijing, Xi'an, and Kunming as compared with those of other Asian populations..Biochemical Genetics,46(9-10),566-582..
MLA Koji Shimizu,et al."Characteristics of the beta-globin gene cluster haplotypes of three Han Chinese populations at Beijing, Xi'an, and Kunming as compared with those of other Asian populations.".Biochemical Genetics 46.9-10(2008):566-582..
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