Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data
Li, Huijie1,2,3; Chan, Raymond C. K.1,2,3,4; McAlonan, Grainne M.4,5; Gong, Qi-yong6
2010-09-01
发表期刊SCHIZOPHRENIA BULLETIN
ISSN0586-7614
文章类型Article
卷号36期号:5页码:1029-1039
摘要Background: People with schizophrenia have difficulty with emotion perception. Functional imaging studies indicate regional brain activation abnormalities in patients with schizophrenia when processing facial emotion. However, findings have not been entirely consistent across different studies. Methods: Activation likelihood estimation (ALE) meta-analyses were conducted to examine brain activation during facial emotion processing in patients with schizophrenia, controls, and patients compared with controls. Secondary meta-analyses were performed to assess the contribution of task design and illness chronicity to the results reported. Results: When processing facial expressions of emotions, both patients with schizophrenia and healthy controls activated the bilateral amygdala and right fusiform gyri. However, the extent of activation in these regions was generally much more limited in the schizophrenia samples. When directly compared with controls, the extent of activation in bilateral amygdala, parahippocampal gyrus and fusiform gyrus, right superior frontal gyrus, and lentiform nucleus was significantly less in patients. Patients with schizophrenia, but not controls, activated the left insula. A relative failure to recruit the amygdala in patients occurred regardless of whether the task design was explicit or implicit, while differences in fusiform activation were evident in explicit, not implicit, tasks. Restricting the analysis to patients with chronic illness did not substantially change the results. Conclusions: A marked underrecruitment of the amygdala, accompanied by a substantial limitation in activation throughout a ventral temporal-basal ganglia-prefrontal cortex "social brain" system may be central to the difficulties patients experience when processing facial emotion.
关键词meta-analysis schizophrenia emotion perception amygdala
学科领域认知神经科学
DOI10.1093/schbul/sbn190.
URL查看原文
收录类别SCI ; SSCI
语种英语
WOS记录号WOS:000281188100019
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/10088
专题中国科学院心理研究所回溯数据库(1956-2010)
作者单位1.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Key Lab Mental Hlth, Beijing 100101, Peoples R China
3.Chinese Acad Sci, Grad Sch, Inst Psychol, Beijing 100101, Peoples R China
4.Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
5.Univ Hong Kong, State Key Lab Brain & Cognit Sci, Hong Kong, Hong Kong, Peoples R China
6.Sichuan Univ, W China Sch Med, W China Hosp, Huaxi MR Res Ctr,Dept Radiol, Chengdu 610064, Peoples R China
推荐引用方式
GB/T 7714
Li, Huijie,Chan, Raymond C. K.,McAlonan, Grainne M.,et al. Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data[J]. SCHIZOPHRENIA BULLETIN,2010,36(5):1029-1039.
APA Li, Huijie,Chan, Raymond C. K.,McAlonan, Grainne M.,&Gong, Qi-yong.(2010).Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data.SCHIZOPHRENIA BULLETIN,36(5),1029-1039.
MLA Li, Huijie,et al."Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data".SCHIZOPHRENIA BULLETIN 36.5(2010):1029-1039.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Facial_Emotion_Proce(330KB) 限制开放CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Li, Huijie]的文章
[Chan, Raymond C. K.]的文章
[McAlonan, Grainne M.]的文章
百度学术
百度学术中相似的文章
[Li, Huijie]的文章
[Chan, Raymond C. K.]的文章
[McAlonan, Grainne M.]的文章
必应学术
必应学术中相似的文章
[Li, Huijie]的文章
[Chan, Raymond C. K.]的文章
[McAlonan, Grainne M.]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Facial_Emotion_Processing_in_Schizophrenia_A_Meta-analysis_of_Functional_Neuroimaging_Data1[1].pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。