Quantile rank maps: A new tool for understanding individual brain development | |
Chen, Huaihou1; Kelly, Clare2; Castellanos, F. Xavier2,3; He, Ye4,5,6,7; Zuo, Xi-Nian5,6,7; Reiss, Philip T.2,3,8; Philip T. Reiss | |
通讯作者邮箱 | phil.reiss@nyumc.org |
心理所单位排序 | 4 |
摘要 | We propose a novel method for neurodevelopmental brain mapping that displays how an individual's values for a quantity of interest compare with age-specific norms. By estimating smoothly age-varying distributions at a set of brain regions of interest, we derive age-dependent region-wise quantile ranks for a given individual, which can be presented in the form of a brain map. Such quantile rank maps could potentially be used for clinical screening. Bootstrap-based confidence intervals are proposed for the quantile rank estimates. We also propose a recalibrated Kolmogorov-Smirnov test for detecting group differences in the age-varying distribution. This test is shown to be more robust to model misspecification than a linear regression-based test. The proposed methods are applied to brain imaging data from the Nathan Kline Institute Rockland Sample and from the Autism Brain Imaging Data Exchange (ABIDE) sample. |
关键词 | Box-Cox transformation Generalized additive models for location scale and shape Quantile rank map MRI Resting-state fMRI Penalized B-splines |
学科领域 | 认知神经科学 |
2015-05-01 | |
语种 | 英语 |
DOI | 10.1016/j.neuroimage.2014.12.082 |
发表期刊 | NEUROIMAGE |
ISSN | 1053-8119 |
卷号 | 111期号:1页码:454-463 |
期刊论文类型 | Article |
URL | 查看原文 |
收录类别 | SCI |
资助项目 | National Institutes of Health grant 1R01MH095836- 01A1 ; National Institutes of Health grant R33MH086952 ; Major Joint Fund for International Cooperation and Exchange of the National Natural Science Foundation (81220108014, XNZ) |
WOS记录号 | WOS:000352224100040 |
资助机构 | National Institutes of Health ; Chinese Academy of Sciences ; National Natural Science Foundation |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/10190 |
专题 | 认知与发展心理学研究室 |
通讯作者 | Philip T. Reiss |
作者单位 | 1.Univ Florida, Coll Med, Coll Publ Hlth & Hlth Profess, Dept Biostat, Gainesville, FL USA 2.NYU, Sch Med, Dept Child & Adolescent Psychiat, New York, NY 10016 USA 3.Nathan S Kline Inst Psychiat Res, Orangeburg, NY 10962 USA 4.Univ Chinese Acad Sci, Beijing, Peoples R China 5.Chinese Acad Sci, Key Lab Behav Sci, Beijing 100101, Peoples R China 6.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China 7.Chinese Acad Sci, Inst Psychol, Lab Funct Connectome & Dev, Beijing 100101, Peoples R China 8.NYU, Sch Med, Dept Populat Hlth, New York, NY USA |
推荐引用方式 GB/T 7714 | Chen, Huaihou,Kelly, Clare,Castellanos, F. Xavier,et al. Quantile rank maps: A new tool for understanding individual brain development[J]. NEUROIMAGE,2015,111(1):454-463. |
APA | Chen, Huaihou.,Kelly, Clare.,Castellanos, F. Xavier.,He, Ye.,Zuo, Xi-Nian.,...&Philip T. Reiss.(2015).Quantile rank maps: A new tool for understanding individual brain development.NEUROIMAGE,111(1),454-463. |
MLA | Chen, Huaihou,et al."Quantile rank maps: A new tool for understanding individual brain development".NEUROIMAGE 111.1(2015):454-463. |
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Quantile rank maps.p(4553KB) | 期刊论文 | 出版稿 | 暂不开放 | CC BY-NC-SA | 请求全文 |
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