PSYCH OpenIR  > 认知与发展心理学研究室
Quantile rank maps: A new tool for understanding individual brain development
Chen, Huaihou1; Kelly, Clare2; Castellanos, F. Xavier2,3; He, Ye4,5,6,7; Zuo, Xi-Nian5,6,7; Reiss, Philip T.2,3,8; Philip T. Reiss
Contribution Rank4

We propose a novel method for neurodevelopmental brain mapping that displays how an individual's values for a quantity of interest compare with age-specific norms. By estimating smoothly age-varying distributions at a set of brain regions of interest, we derive age-dependent region-wise quantile ranks for a given individual, which can be presented in the form of a brain map. Such quantile rank maps could potentially be used for clinical screening. Bootstrap-based confidence intervals are proposed for the quantile rank estimates. We also propose a recalibrated Kolmogorov-Smirnov test for detecting group differences in the age-varying distribution. This test is shown to be more robust to model misspecification than a linear regression-based test. The proposed methods are applied to brain imaging data from the Nathan Kline Institute Rockland Sample and from the Autism Brain Imaging Data Exchange (ABIDE) sample.

KeywordBox-Cox transformation Generalized additive models for location scale and shape Quantile rank map MRI Resting-state fMRI Penalized B-splines
Subject Area认知神经科学
Source PublicationNEUROIMAGE
Indexed BySCI
Funding ProjectNational Institutes of Health grant 1R01MH095836- 01A1 ; National Institutes of Health grant R33MH086952 ; Major Joint Fund for International Cooperation and Exchange of the National Natural Science Foundation (81220108014, XNZ)
WOS IDWOS:000352224100040
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Corresponding AuthorPhilip T. Reiss
Affiliation1.Univ Florida, Coll Med, Coll Publ Hlth & Hlth Profess, Dept Biostat, Gainesville, FL USA
2.NYU, Sch Med, Dept Child & Adolescent Psychiat, New York, NY 10016 USA
3.Nathan S Kline Inst Psychiat Res, Orangeburg, NY 10962 USA
4.Univ Chinese Acad Sci, Beijing, Peoples R China
5.Chinese Acad Sci, Key Lab Behav Sci, Beijing 100101, Peoples R China
6.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China
7.Chinese Acad Sci, Inst Psychol, Lab Funct Connectome & Dev, Beijing 100101, Peoples R China
8.NYU, Sch Med, Dept Populat Hlth, New York, NY USA
Recommended Citation
GB/T 7714
Chen, Huaihou,Kelly, Clare,Castellanos, F. Xavier,et al. Quantile rank maps: A new tool for understanding individual brain development[J]. NEUROIMAGE,2015,111(1):454-463.
APA Chen, Huaihou.,Kelly, Clare.,Castellanos, F. Xavier.,He, Ye.,Zuo, Xi-Nian.,...&Philip T. Reiss.(2015).Quantile rank maps: A new tool for understanding individual brain development.NEUROIMAGE,111(1),454-463.
MLA Chen, Huaihou,et al."Quantile rank maps: A new tool for understanding individual brain development".NEUROIMAGE 111.1(2015):454-463.
Files in This Item:
File Name/Size DocType Version Access License
Quantile rank maps.p(4553KB)期刊论文出版稿暂不开放CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Chen, Huaihou]'s Articles
[Kelly, Clare]'s Articles
[Castellanos, F. Xavier]'s Articles
Baidu academic
Similar articles in Baidu academic
[Chen, Huaihou]'s Articles
[Kelly, Clare]'s Articles
[Castellanos, F. Xavier]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Chen, Huaihou]'s Articles
[Kelly, Clare]'s Articles
[Castellanos, F. Xavier]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.