Institutional Repository, Institute of Psychology, Chinese Academy of Sciences
Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia | |
Lam, Joanna W. S.1; Lui, Simon S. Y.1,2,3; Wang, Ya2,3; Chan, Raymond C. K.2,3; Cheung, Eric F. C.1; Cheung, EFC (reprint author), Castle Peak Hosp, Tuen Mun, Hong Kong, Peoples R China. | |
心理所单位排序 | 2 |
摘要 | Background: Prospective memory (PM), the ability to remember to carry out an intended action in the future, is thought to relate closely to everyday functioning, such as medication adherence. PM impairment in schizophrenia may contribute to unintentional medication non-adherence. This study aimed to examine the relationship between PM, medication management and medication adherence. Methods: Eighty-two stable patients with schizophrenia underwent assessment for PM and medication management ability by laboratory measures at baseline. Clinical symptoms, other neuropsychological functions and risk factors known to associate with non-adherence were also measured. Linear regression was used to identify predictors of medication management ability at baseline. Actual medication adherence was assessed three months later and logistic regression was used to identify predictors of non-adherence. Results: In the linear regression model, time-and event-based PM together accounted for 72.3% of the variance in the performance of medication management at baseline. At three-month follow-up, the non-adherent group performed significantly more poorly in time-and event-based PM, and had poorer insight, more severe symptoms and poorer ability to manage medications, as compared to the adherent group. In the logistic regression model, insight and PANSS general score significantly predicted non-adherence in the community. Time- and event-based PM moderated the predictive power of insight and PANSS general score. Conclusions: Our results support that PM performance robustly predicts medication management ability and may influence medication adherence in the community by moderating the effect of insight and symptom severity. Optimizing PM performance may improve medication adherence in the community, particularly for unintentional non-adherence. (C) 2013 Elsevier B. V. All rights reserved. |
关键词 | Schizophrenia Prospective memory Medication management Treatment adherence |
学科领域 | Abnormal Psychology |
2013 | |
语种 | 英语 |
发表期刊 | SCHIZOPHRENIA RESEARCH |
ISSN | 0586-7614 |
卷号 | 147期号:2014-02-03页码:293-300 |
期刊论文类型 | 期刊论文 |
URL | 查看原文 |
收录类别 | SCI |
项目简介 | This study was supported partially by grants from the Key Laboratory of Mental Health, Institute of Psychology, and the Knowledge Innovation Project of the Chinese Academy of Sciences (KSCX2-EW-J-8). These funding agents had no further role in the study design; in the collection, analysis and interpretation of the data; in the writing of the manuscript; and in the decision to submit the paper for publication. |
WOS记录号 | WOS:000320598700013 |
资助机构 | Key Laboratory of Mental Health, Institute of Psychology ; Chinese Academy of Sciences [KSCX2-EW-J-8] |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/10621 |
专题 | 脑与认知科学国家重点实验室 |
通讯作者 | Cheung, EFC (reprint author), Castle Peak Hosp, Tuen Mun, Hong Kong, Peoples R China. |
作者单位 | 1.Castle Peak Hosp, Tuen Mun, Hong Kong, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Lam, Joanna W. S.,Lui, Simon S. Y.,Wang, Ya,et al. Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia[J]. SCHIZOPHRENIA RESEARCH,2013,147(2014-02-03):293-300. |
APA | Lam, Joanna W. S.,Lui, Simon S. Y.,Wang, Ya,Chan, Raymond C. K.,Cheung, Eric F. C.,&Cheung, EFC .(2013).Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia.SCHIZOPHRENIA RESEARCH,147(2014-02-03),293-300. |
MLA | Lam, Joanna W. S.,et al."Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia".SCHIZOPHRENIA RESEARCH 147.2014-02-03(2013):293-300. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
WOS_000320598700013.(184KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论