PSYCH OpenIR  > 脑与认知科学国家重点实验室
Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia
Lam, Joanna W. S.1; Lui, Simon S. Y.1,2,3; Wang, Ya2,3; Chan, Raymond C. K.2,3; Cheung, Eric F. C.1; Cheung, EFC (reprint author), Castle Peak Hosp, Tuen Mun, Hong Kong, Peoples R China.
2013
Source PublicationSCHIZOPHRENIA RESEARCH
ISSN0586-7614
Subtype期刊论文
Volume147Issue:2014-02-03Pages:293-300
Contribution Rank2
AbstractBackground: Prospective memory (PM), the ability to remember to carry out an intended action in the future, is thought to relate closely to everyday functioning, such as medication adherence. PM impairment in schizophrenia may contribute to unintentional medication non-adherence. This study aimed to examine the relationship between PM, medication management and medication adherence. Methods: Eighty-two stable patients with schizophrenia underwent assessment for PM and medication management ability by laboratory measures at baseline. Clinical symptoms, other neuropsychological functions and risk factors known to associate with non-adherence were also measured. Linear regression was used to identify predictors of medication management ability at baseline. Actual medication adherence was assessed three months later and logistic regression was used to identify predictors of non-adherence. Results: In the linear regression model, time-and event-based PM together accounted for 72.3% of the variance in the performance of medication management at baseline. At three-month follow-up, the non-adherent group performed significantly more poorly in time-and event-based PM, and had poorer insight, more severe symptoms and poorer ability to manage medications, as compared to the adherent group. In the logistic regression model, insight and PANSS general score significantly predicted non-adherence in the community. Time- and event-based PM moderated the predictive power of insight and PANSS general score. Conclusions: Our results support that PM performance robustly predicts medication management ability and may influence medication adherence in the community by moderating the effect of insight and symptom severity. Optimizing PM performance may improve medication adherence in the community, particularly for unintentional non-adherence. (C) 2013 Elsevier B. V. All rights reserved.
KeywordSchizophrenia Prospective memory Medication management Treatment adherence
Subject AreaAbnormal Psychology
URL查看原文
Indexed BySCI
Language英语
Funding OrganizationKey Laboratory of Mental Health, Institute of Psychology ; Chinese Academy of Sciences [KSCX2-EW-J-8]
Project Intro.This study was supported partially by grants from the Key Laboratory of Mental Health, Institute of Psychology, and the Knowledge Innovation Project of the Chinese Academy of Sciences (KSCX2-EW-J-8). These funding agents had no further role in the study design; in the collection, analysis and interpretation of the data; in the writing of the manuscript; and in the decision to submit the paper for publication.
WOS IDWOS:000320598700013
Citation statistics
Cited Times:17[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/10621
Collection脑与认知科学国家重点实验室
Corresponding AuthorCheung, EFC (reprint author), Castle Peak Hosp, Tuen Mun, Hong Kong, Peoples R China.
Affiliation1.Castle Peak Hosp, Tuen Mun, Hong Kong, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing, Peoples R China
3.Univ Chinese Acad Sci, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Lam, Joanna W. S.,Lui, Simon S. Y.,Wang, Ya,et al. Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia[J]. SCHIZOPHRENIA RESEARCH,2013,147(2014-02-03):293-300.
APA Lam, Joanna W. S.,Lui, Simon S. Y.,Wang, Ya,Chan, Raymond C. K.,Cheung, Eric F. C.,&Cheung, EFC .(2013).Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia.SCHIZOPHRENIA RESEARCH,147(2014-02-03),293-300.
MLA Lam, Joanna W. S.,et al."Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia".SCHIZOPHRENIA RESEARCH 147.2014-02-03(2013):293-300.
Files in This Item:
File Name/Size DocType Version Access License
WOS_000320598700013.(184KB)期刊论文出版稿限制开放CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Lam, Joanna W. S.]'s Articles
[Lui, Simon S. Y.]'s Articles
[Wang, Ya]'s Articles
Baidu academic
Similar articles in Baidu academic
[Lam, Joanna W. S.]'s Articles
[Lui, Simon S. Y.]'s Articles
[Wang, Ya]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Lam, Joanna W. S.]'s Articles
[Lui, Simon S. Y.]'s Articles
[Wang, Ya]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: WOS_000320598700013.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.