PSYCH OpenIR  > 中国科学院行为科学重点实验室
Chronic stress exposure decreases the cortisol awakening response in healthy young men
Duan, Hongxia1; Yuan, Yiran1; Zhang, Liang1; Qin, Shaozheng2,3; Zhang, Kan1; Buchanan, Tony W.4; Wu, Jianhui1; Wu, JH (reprint author), Chinese Acad Sci, Inst Psychol, 16 Lincui Rd, Beijing 100101, Peoples R China.
2013
Source PublicationSTRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
ISSN1532-3005
Subtype期刊论文
Volume16Issue:6Pages:630-637
Contribution Rank1
AbstractAcademic examination is a major stressor for students in China. Investigation of stress-sensitive endocrine responses to major examination stress serves as a good model of naturalistic chronic psychological stress in an otherwise healthy population. The cortisol awakening response (CAR) is an endocrine marker of the hypothalamic-pituitary-adrenocortical (HPA) axis in response to stress. However, it remains unknown how chronic examination stress impacts the CAR in a young healthy population To exclude the influence of sex effects on hormone level, the CAR and psychological stress responses were assessed on two consecutive workdays in 42 male participants during their preparations for the Chinese National Postgraduate Entrance Exam (NPEE) and 21 non-exam, age-matched male comparisons. On each day, four saliva samples were collected immediately after awakening, 15 minutes, 30 minutes and 60 minutes after awakening. The waking level (S1), the increase within 30 minutes after awakening (R-30), the area under the curve with respect to ground (AUC(g)), and the area under the curve with respect to increase (AUC(i)) were used to quantify the CAR. Psychological stress and anxiety were assessed by the Perceived Stress Scale and the Spielberger State-Trait Anxiety Inventory, respectively. Male participants in the exam group had greater perceived stress and anxiety scores relatibe to the non-exam group. Both R-30 and AUC(i) in the exam group were significantly lower than the comparison group and this effect was most pronounced for participants with high levels of perceived stress in the exam group. Perceived stress and anxiety levels were negatively correlated with both R-30 and AUC(i). Chronic examination stress can lead to the decrease of CAR in healthy young men, possibly due to reduced HPA axis activity under long-term sustained stress.
KeywordChronic stress cortisol awakening response exam hypoactivity hypothalamic-pituitary-adrenocortical axis male
Subject AreaHealth Psychology
URL查看原文
Indexed BySCI
Language英语
Funding OrganizationNSF China [91124003, 90924017, 31100734] ; Excellent Young Scientists Fund, IP, CAS [YICX63S03]
Project Intro.This work was supported by the NSF China (91124003,90924017,31100734) and the Excellent Young Scientists Fund, IP, CAS (YICX63S03).
WOS Research AreaBehavioral Sciences ; Endocrinology & Metabolism ; Neurosciences & Neurology
WOS SubjectBehavioral Sciences ; Endocrinology & Metabolism ; Neurosciences
WOS IDWOS:000325500800005
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordCHRONIC-FATIGUE-SYNDROME ; PITUITARY-ADRENAL AXIS ; SALIVARY CORTISOL ; ACADEMIC EXAMINATION ; PSYCHOSOCIAL STRESS ; SAMPLING COMPLIANCE ; POLICE OFFICERS ; MENSTRUAL-CYCLE ; EXPERIENCE ; HYPOCORTISOLISM
Citation statistics
Cited Times:20[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/10714
Collection中国科学院行为科学重点实验室
Corresponding AuthorWu, JH (reprint author), Chinese Acad Sci, Inst Psychol, 16 Lincui Rd, Beijing 100101, Peoples R China.
Affiliation1.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China
2.Stanford Univ, Sch Med, Dept Psychiat, Stanford, CA 94305 USA
3.Stanford Univ, Sch Med, Dept Behav Sci, Stanford, CA 94305 USA
4.St Louis Univ, Dept Psychol, St Louis, MO 63103 USA
Recommended Citation
GB/T 7714
Duan, Hongxia,Yuan, Yiran,Zhang, Liang,et al. Chronic stress exposure decreases the cortisol awakening response in healthy young men[J]. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS,2013,16(6):630-637.
APA Duan, Hongxia.,Yuan, Yiran.,Zhang, Liang.,Qin, Shaozheng.,Zhang, Kan.,...&Wu, JH .(2013).Chronic stress exposure decreases the cortisol awakening response in healthy young men.STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS,16(6),630-637.
MLA Duan, Hongxia,et al."Chronic stress exposure decreases the cortisol awakening response in healthy young men".STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS 16.6(2013):630-637.
Files in This Item:
File Name/Size DocType Version Access License
WOS000325500800005.p(365KB) 限制开放Apache LicenseView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Duan, Hongxia]'s Articles
[Yuan, Yiran]'s Articles
[Zhang, Liang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Duan, Hongxia]'s Articles
[Yuan, Yiran]'s Articles
[Zhang, Liang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Duan, Hongxia]'s Articles
[Yuan, Yiran]'s Articles
[Zhang, Liang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: WOS000325500800005.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.