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The Role of Interoception and Insular Cortex in Addiction
Li Chun-Lu1,2; Zhu Ning1; Li Yong-Hui1; Meng Xiao-Lu1,2; Gao Jun1,2; Sui Nan1
2013
Source PublicationPROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
SubtypeArticle
Volume40Issue:1Pages:15-21
AbstractInteroception is the sense of the physiological condition of the body. Recent studies suggested that interoception is involved in drug addiction and insular cortex is a key anatomical position. The neural mechanisms underlying such phenomena attract growing attention. In an effort to develop working hypotheses for future investigation, the article first reviewed the evidence of interoceptive regulation of addiction, and subsequently presented human and animal data that suggest a central role of the insular cortex in mediating interoception and addiction. On this basis, we proposed potential neurobiological mechanisms through which insular cortex may mediate drug addiction. Further, possible functional roles of neurotransmitters in the insular cortex are discussed in the context of drug addiction.
Keywordinteroception insular cortex addiction
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Biophysics
WOS SubjectBiochemistry & Molecular Biology ; Biophysics
WOS IDWOS:000314003100002
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordTAKING DECISION-MAKING ; FUNCTIONAL CONNECTIVITY ; NUCLEUS-ACCUMBENS ; VISCERAL CORTEX ; DRUG-ADDICTION ; RAT ; ACTIVATION ; BRAIN ; RISK ; STOP
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/10804
Collection中国科学院心理健康重点实验室
Affiliation1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
First Author AffilicationKey Laboratory of Mental Health, CAS
Recommended Citation
GB/T 7714
Li Chun-Lu,Zhu Ning,Li Yong-Hui,et al. The Role of Interoception and Insular Cortex in Addiction[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2013,40(1):15-21.
APA Li Chun-Lu,Zhu Ning,Li Yong-Hui,Meng Xiao-Lu,Gao Jun,&Sui Nan.(2013).The Role of Interoception and Insular Cortex in Addiction.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,40(1),15-21.
MLA Li Chun-Lu,et al."The Role of Interoception and Insular Cortex in Addiction".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 40.1(2013):15-21.
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