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The Role of Interoception and Insular Cortex in Addiction
Li Chun-Lu1,2; Zhu Ning1; Li Yong-Hui1; Meng Xiao-Lu1,2; Gao Jun1,2; Sui Nan1
2013
发表期刊PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
文章类型Article
卷号40期号:1页码:15-21
摘要Interoception is the sense of the physiological condition of the body. Recent studies suggested that interoception is involved in drug addiction and insular cortex is a key anatomical position. The neural mechanisms underlying such phenomena attract growing attention. In an effort to develop working hypotheses for future investigation, the article first reviewed the evidence of interoceptive regulation of addiction, and subsequently presented human and animal data that suggest a central role of the insular cortex in mediating interoception and addiction. On this basis, we proposed potential neurobiological mechanisms through which insular cortex may mediate drug addiction. Further, possible functional roles of neurotransmitters in the insular cortex are discussed in the context of drug addiction.
关键词interoception insular cortex addiction
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Biophysics
WOS类目Biochemistry & Molecular Biology ; Biophysics
WOS记录号WOS:000314003100002
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]TAKING DECISION-MAKING ; FUNCTIONAL CONNECTIVITY ; NUCLEUS-ACCUMBENS ; VISCERAL CORTEX ; DRUG-ADDICTION ; RAT ; ACTIVATION ; BRAIN ; RISK ; STOP
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/10804
专题中国科学院心理健康重点实验室
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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GB/T 7714
Li Chun-Lu,Zhu Ning,Li Yong-Hui,et al. The Role of Interoception and Insular Cortex in Addiction[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2013,40(1):15-21.
APA Li Chun-Lu,Zhu Ning,Li Yong-Hui,Meng Xiao-Lu,Gao Jun,&Sui Nan.(2013).The Role of Interoception and Insular Cortex in Addiction.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,40(1),15-21.
MLA Li Chun-Lu,et al."The Role of Interoception and Insular Cortex in Addiction".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 40.1(2013):15-21.
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