Adaptive influence of long term high altitude residence on spatial working memory: An fMRI study

	Adaptive influence of long term high altitude residence on spatial working memory: An fMRI study
	Yan, Xiaodan 2,3,4; Zhang, Jiaxing 1,2; Gong, Qiyong 5; Weng, Xuchu2 ; Zhang, JX (reprint author), Xiamen Univ, Dept Physiol, Coll Med, Xiamen, Peoples R China.
心理所单位排序	1
摘要	With an increasing population living at a high altitude (HA), the impact of HA residence on human cognitive function has raised concerns. We recruited two groups of college students with one group born and grew up at HA until early adulthood and the control group born and grew up at near sea level (SL); the two groups were matched at age, gender ratio, educational level, the ancestral lines, and peripheral physiology (especially the hemoglobin concentration). A 2-back spatial working memory task was performed by each subject in the scanner while fMRI data were acquired. Compared to the SL control group, the HA group showed equal response accuracy, with more variance in reaction time and a larger average value. fMRI data indicated that both groups showed common activation patterns in the neural pathway typically associated with working memory. The HA group had greater activation at the left pyramis, the left superior temporal gyrus and less activation at the left middle occipital gyrus. Significant correlations were found within each group between the reaction times and BOLD signal change amplitudes at the frontal cortex and the precentral cortex. (C) 2011 Elsevier Inc. All rights reserved.
关键词	Spatial working memory n-Back fMRI Compensation
学科领域	Cognitive Psychology，environmental Psychology
	2011-10-01
语种	英语
发表期刊	BRAIN AND COGNITION
ISSN	0278-2626
卷号	77 期号:1 页码:53-59
期刊论文类型	Article
URL	查看原文
收录类别	SCI ; SSCI
WOS记录号	WOS:000294378000008
引用统计	被引频次：51[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/10864
专题	中国科学院心理健康重点实验室
通讯作者	Zhang, JX (reprint author), Xiamen Univ, Dept Physiol, Coll Med, Xiamen, Peoples R China.
作者单位	1.Xiamen Univ, Dept Physiol, Coll Med, Xiamen, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Lab Higher Brain Funct, Beijing 100101, Peoples R China 3.Rensselaer Polytech Inst, Dept Cognit Sci, Troy, NY USA 4.NYU, Ctr Biomed Imaging, New York, NY USA 5.Sichuan Univ, W China Hosp, Huaxi Magnet Resonance Res Ctr, Chengdu 610064, Peoples R China
第一作者单位	中国科学院心理研究所
推荐引用方式 GB/T 7714	Yan, Xiaodan,Zhang, Jiaxing,Gong, Qiyong,et al. Adaptive influence of long term high altitude residence on spatial working memory: An fMRI study[J]. BRAIN AND COGNITION,2011,77(1):53-59.
APA	Yan, Xiaodan,Zhang, Jiaxing,Gong, Qiyong,Weng, Xuchu,&Zhang, JX .(2011).Adaptive influence of long term high altitude residence on spatial working memory: An fMRI study.BRAIN AND COGNITION,77(1),53-59.
MLA	Yan, Xiaodan,et al."Adaptive influence of long term high altitude residence on spatial working memory: An fMRI study".BRAIN AND COGNITION 77.1(2011):53-59.

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