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ADHDgene: a genetic database for attention deficit hyperactivity disorder
Zhang, Liuyan1,2; Chang, Suhua1,2; Li, Zhao1,2; Zhang, Kunlin1; Du, Yang1,2; Ott, Jurg1; Wang, Jing1; Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
2012
Source PublicationNUCLEIC ACIDS RESEARCH
ISSN0305-1048
SubtypeArticle
Volume40Issue:D1Pages:D1003-D1009
Contribution Rank1
AbstractWith a worldwide prevalence of similar to 5%, attention deficit hyperactivity disorder (ADHD) has become one of the most common psychiatric disorders. The polygenetic nature of ADHD indicates that multiple genes jointly contribute to the development of this complex disease. Studies aiming to explore genetic susceptibility of ADHD have been increasing in recent years. There is a growing need to integrate the genetic data from various genetic studies to provide a comprehensive data set and uniform access for convenience of in-depth data mining. So far, there has been no such effort for ADHD. To address the genetic complexity of ADHD, we developed the ADHDgene database by integrating ADHD-related genetic factors by profound literature reading. Based on the data from the literature, extended functional analysis, including linkage disequilibrium analysis, pathway-based analysis and gene mapping were performed to provide new insights into genetic causes of ADHD. Moreover, powerful search tools and a graphical browser were developed to facilitate the navigation of the data and data connections. As the first genetic database for ADHD, ADHDgene aims to provide researchers with a central genetic resource and analysis platform for ADHD and is freely available at http://adhd.psych.ac.cn/.
Subject AreaDevelopmental Psychology, Medical Psychology
URL查看原文
Indexed BySCI
Language英语
Funding OrganizationChinese Academy of Sciences [KSCX2-EW-J-8] ; National Natural Science Foundation of China [81101545]
Project Intro.Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-J-8); National Natural Science Foundation of China (81101545). Funding for open access charge: Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-J-8). The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors.
WOS IDWOS:000298601300150
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Cited Times:30[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/10865
Collection中国科学院心理健康重点实验室
Corresponding AuthorWang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
Affiliation1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
First Author AffilicationKey Laboratory of Mental Health, CAS
Recommended Citation
GB/T 7714
Zhang, Liuyan,Chang, Suhua,Li, Zhao,et al. ADHDgene: a genetic database for attention deficit hyperactivity disorder[J]. NUCLEIC ACIDS RESEARCH,2012,40(D1):D1003-D1009.
APA Zhang, Liuyan.,Chang, Suhua.,Li, Zhao.,Zhang, Kunlin.,Du, Yang.,...&Wang, J .(2012).ADHDgene: a genetic database for attention deficit hyperactivity disorder.NUCLEIC ACIDS RESEARCH,40(D1),D1003-D1009.
MLA Zhang, Liuyan,et al."ADHDgene: a genetic database for attention deficit hyperactivity disorder".NUCLEIC ACIDS RESEARCH 40.D1(2012):D1003-D1009.
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