Institutional Repository of Key Laboratory of Mental Health, CAS
| ADHDgene: a genetic database for attention deficit hyperactivity disorder | |
Zhang, Liuyan1,2 ; Chang, Suhua1,2; Li, Zhao1,2; Zhang, Kunlin1; Du, Yang1,2; Ott, Jurg1; Wang, Jing1; Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
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| 心理所单位排序 | 1 |
| 摘要 | With a worldwide prevalence of similar to 5%, attention deficit hyperactivity disorder (ADHD) has become one of the most common psychiatric disorders. The polygenetic nature of ADHD indicates that multiple genes jointly contribute to the development of this complex disease. Studies aiming to explore genetic susceptibility of ADHD have been increasing in recent years. There is a growing need to integrate the genetic data from various genetic studies to provide a comprehensive data set and uniform access for convenience of in-depth data mining. So far, there has been no such effort for ADHD. To address the genetic complexity of ADHD, we developed the ADHDgene database by integrating ADHD-related genetic factors by profound literature reading. Based on the data from the literature, extended functional analysis, including linkage disequilibrium analysis, pathway-based analysis and gene mapping were performed to provide new insights into genetic causes of ADHD. Moreover, powerful search tools and a graphical browser were developed to facilitate the navigation of the data and data connections. As the first genetic database for ADHD, ADHDgene aims to provide researchers with a central genetic resource and analysis platform for ADHD and is freely available at http://adhd.psych.ac.cn/. |
| 学科领域 | Developmental Psychology， Medical Psychology |
| 2012 | |
| 语种 | 英语 |
| 发表期刊 | NUCLEIC ACIDS RESEARCH
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| ISSN | 0305-1048 |
| 卷号 | 40期号:D1页码:D1003-D1009 |
| 期刊论文类型 | Article |
| URL | 查看原文 |
| 收录类别 | SCI |
| 项目简介 | Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-J-8); National Natural Science Foundation of China (81101545). Funding for open access charge: Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-J-8). The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors. |
| WOS记录号 | WOS:000298601300150 |
| 资助机构 | Chinese Academy of Sciences [KSCX2-EW-J-8] ; National Natural Science Foundation of China [81101545] |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.psych.ac.cn/handle/311026/10865 |
| 专题 | 中国科学院心理健康重点实验室 |
| 通讯作者 | Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China. |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 第一作者单位 | 中国科学院心理健康重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhang, Liuyan,Chang, Suhua,Li, Zhao,et al. ADHDgene: a genetic database for attention deficit hyperactivity disorder[J]. NUCLEIC ACIDS RESEARCH,2012,40(D1):D1003-D1009. |
| APA | Zhang, Liuyan.,Chang, Suhua.,Li, Zhao.,Zhang, Kunlin.,Du, Yang.,...&Wang, J .(2012).ADHDgene: a genetic database for attention deficit hyperactivity disorder.NUCLEIC ACIDS RESEARCH,40(D1),D1003-D1009. |
| MLA | Zhang, Liuyan,et al."ADHDgene: a genetic database for attention deficit hyperactivity disorder".NUCLEIC ACIDS RESEARCH 40.D1(2012):D1003-D1009. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| WOS000298601300150.p（3004KB） | 期刊论文 | 出版稿 | 限制开放 | Apache License | 请求全文 | |
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