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ADHDgene: a genetic database for attention deficit hyperactivity disorder
Zhang, Liuyan1,2; Chang, Suhua1,2; Li, Zhao1,2; Zhang, Kunlin1; Du, Yang1,2; Ott, Jurg1; Wang, Jing1; Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
2012
发表期刊NUCLEIC ACIDS RESEARCH
ISSN0305-1048
文章类型Article
卷号40期号:D1页码:D1003-D1009
产权排序1
摘要With a worldwide prevalence of similar to 5%, attention deficit hyperactivity disorder (ADHD) has become one of the most common psychiatric disorders. The polygenetic nature of ADHD indicates that multiple genes jointly contribute to the development of this complex disease. Studies aiming to explore genetic susceptibility of ADHD have been increasing in recent years. There is a growing need to integrate the genetic data from various genetic studies to provide a comprehensive data set and uniform access for convenience of in-depth data mining. So far, there has been no such effort for ADHD. To address the genetic complexity of ADHD, we developed the ADHDgene database by integrating ADHD-related genetic factors by profound literature reading. Based on the data from the literature, extended functional analysis, including linkage disequilibrium analysis, pathway-based analysis and gene mapping were performed to provide new insights into genetic causes of ADHD. Moreover, powerful search tools and a graphical browser were developed to facilitate the navigation of the data and data connections. As the first genetic database for ADHD, ADHDgene aims to provide researchers with a central genetic resource and analysis platform for ADHD and is freely available at http://adhd.psych.ac.cn/.
学科领域Developmental Psychology, Medical Psychology
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收录类别SCI
语种英语
项目资助者Chinese Academy of Sciences [KSCX2-EW-J-8] ; National Natural Science Foundation of China [81101545]
项目简介Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-J-8); National Natural Science Foundation of China (81101545). Funding for open access charge: Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-J-8). The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors.
WOS记录号WOS:000298601300150
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文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/10865
专题中国科学院心理健康重点实验室
通讯作者Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
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GB/T 7714
Zhang, Liuyan,Chang, Suhua,Li, Zhao,et al. ADHDgene: a genetic database for attention deficit hyperactivity disorder[J]. NUCLEIC ACIDS RESEARCH,2012,40(D1):D1003-D1009.
APA Zhang, Liuyan.,Chang, Suhua.,Li, Zhao.,Zhang, Kunlin.,Du, Yang.,...&Wang, J .(2012).ADHDgene: a genetic database for attention deficit hyperactivity disorder.NUCLEIC ACIDS RESEARCH,40(D1),D1003-D1009.
MLA Zhang, Liuyan,et al."ADHDgene: a genetic database for attention deficit hyperactivity disorder".NUCLEIC ACIDS RESEARCH 40.D1(2012):D1003-D1009.
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