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Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study
Jutras-Aswad, Didier1; Jacobs, Michelle M.1,2; Yiannoulos, Georgia1; Roussos, Panos1; Bitsios, Panos3; Nomura, Yoko1,5; Liu, Xun1,4; Hurd, Yasmin L.1,3,6,7; Jutras-Aswad, D (reprint author), Univ Montreal, Dept Psychiat, Montreal, PQ H3C 3J7, Canada.
2012-06-22
发表期刊PLOS ONE
ISSN1932-6203
文章类型Article
卷号7期号:6
产权排序5
摘要Background: Many young people experiment with cannabis, yet only a subgroup progress to dependence suggesting individual differences that could relate to factors such as genetics and behavioral traits. Dopamine receptor D2 (DRD2) and proenkephalin (PENK) genes have been implicated in animal studies with cannabis exposure. Whether polymorphisms of these genes are associated with cannabis dependence and related behavioral traits is unknown.
学科领域Medical Psychology
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收录类别SCI
语种英语
项目资助者Mount Sinai School of Medicine Fund ; Centre Hospitalier de l'Universite de Montreal Research Fellowship Award ; National Institutes of Health [DA15446, T32 DA007135]
项目简介This research was supported by Mount Sinai School of Medicine Fund (YLH), Centre Hospitalier de l'Universite de Montreal Research Fellowship Award (DJA) and National Institutes of Health [DA15446 (YLH), T32 DA007135 (MMJ)]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
WOS记录号WOS:000305730900038
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文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/11431
专题认知与发展心理学研究室
通讯作者Jutras-Aswad, D (reprint author), Univ Montreal, Dept Psychiat, Montreal, PQ H3C 3J7, Canada.
作者单位1.Mt Sinai Sch Med, Dept Psychiat, New York, NY USA
2.Mt Sinai Sch Med, Dept Pharmacol & Syst Therapeut, New York, NY USA
3.Univ Crete, Fac Med, Dept Psychiat & Behav Sci, Iraklion, Crete, Greece
4.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China
5.Queens Coll, Dept Psychol, Queens, NY USA
6.Mt Sinai Sch Med, Dept Neurosci, New York, NY USA
7.James J Peters VA Med Ctr, New York, NY USA
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Jutras-Aswad, Didier,Jacobs, Michelle M.,Yiannoulos, Georgia,et al. Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study[J]. PLOS ONE,2012,7(6).
APA Jutras-Aswad, Didier.,Jacobs, Michelle M..,Yiannoulos, Georgia.,Roussos, Panos.,Bitsios, Panos.,...&Jutras-Aswad, D .(2012).Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study.PLOS ONE,7(6).
MLA Jutras-Aswad, Didier,et al."Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study".PLOS ONE 7.6(2012).
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