Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks

	Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks
	Jiang, Juan1,3 ; He, Xingu 1,3; Wang, Meng-Ya 2; Sui, Nan1 ; Sui, N (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
心理所单位排序	1
摘要	Based on our previous findings in day-old chicks with prenatal morphine-treated, embryonic days 5-8 is crucial for functional development of learning and memory, the underlying structure and cellular mechanisms were further explored. The prenatal morphine-exposed chicks showed deficits in passive avoidance learning and conditioned place preference, and attenuation in paired-pulse facilitation and heterosynaptic long-term potentiation in intermediate medial mesopallium (IMM) in vitro. These results suggest the altered synaptic plasticity of IMM by prenatal morphine exposure is involved in behavioral impairments. (C) 2011 Elsevier B.V. All rights reserved.
关键词	Prenatal morphine exposure Passive avoidance learning (PAL) Conditioned place preference (CPP) Paired-pulse facilitation (PPF) Long-term potentiation (LTP) Intermediate medial mesopallium (IMM)
学科领域	Physiological Psychology/biological Psychology
	2011-06-01
语种	英语
发表期刊	BEHAVIOURAL BRAIN RESEARCH
ISSN	0166-4328
卷号	219 期号:2 页码:363-366
期刊论文类型	Article
收录类别	SCI
项目简介	This work was supported by CNBRP (2009CB522002), CNNSF (30770719), IG-CAS (KSCXI-TW-R-68) to N. Sui, AP-NSF (090413084) to M.Y. Wang and the VPSISG-CAS (2010TIS13) to Stephen Brimijoin. We also thank Y.H. Li, X.Y. Yang and B.A. Wang for their suggestions and technical assistance.
WOS记录号	WOS:000289703700025
资助机构	CNBRP [2009CB522002] ; CNNSF [30770719] ; IG-CAS [KSCXI-TW-R-68] ; AP-NSF [090413084] ; VPSISG-CAS [2010TIS13]
引用统计	被引频次：10[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/11480
专题	中国科学院心理健康重点实验室
通讯作者	Sui, N (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Wannan Med Coll, Cell Electrophysiol Lab, Wuhu 241002, Anhui, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
第一作者单位	中国科学院心理健康重点实验室
推荐引用方式 GB/T 7714	Jiang, Juan,He, Xingu,Wang, Meng-Ya,et al. Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks[J]. BEHAVIOURAL BRAIN RESEARCH,2011,219(2):363-366.
APA	Jiang, Juan,He, Xingu,Wang, Meng-Ya,Sui, Nan,&Sui, N .(2011).Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks.BEHAVIOURAL BRAIN RESEARCH,219(2),363-366.
MLA	Jiang, Juan,et al."Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks".BEHAVIOURAL BRAIN RESEARCH 219.2(2011):363-366.

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