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| Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction | |
Fang, Kechi2 ; Zhao, Hansheng2,3; Sun, Changyue2; Lam, Carolyn M. C.1; Chang, Suhua2,4; Zhang, Kunlin2; Panda, Gurudutta1; Godinho, Miguel1,5; dos Santos, Vitor A. P. Martins1,6; Wang, Jing2; dos Santos, VAPM (reprint author), Helmholtz Ctr Infect Res HZI, Syst & Synthet Biol Grp, Inhoffenstr 7, D-38124 Braunschweig, Germany.
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| 心理所单位排序 | 1 |
| 摘要 | Background: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection. Strain B. cenocepacia J2315 is the most infectious isolate from CF patients. There is a strong demand to reconstruct a genome-scale metabolic network of B. cenocepacia J2315 to systematically analyze its metabolic capabilities and its virulence traits, and to search for potential clinical therapy targets. |
| 学科领域 | Medical Psychology |
| 2011-05-25 | |
| 语种 | 英语 |
| 发表期刊 | BMC SYSTEMS BIOLOGY
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| ISSN | 1752-0509 |
| 卷号 | 5 |
| 期刊论文类型 | Article |
| URL | 查看原文 |
| 收录类别 | SCI |
| 项目简介 | We acknowledge funding from the European Union (Projects PROBACTYS: Grant No. 29104 and MICROME: No. 222886), the National Basic Research Program of China (973 Program) (Grant No. 2011CBA00802) from the Ministry of Science and Technology of the People's Republic of China, the Project for Young Scientists Fund, Institute of Psychology, Chinese Academy of Sciences (Grant No. O9CX115011), and Portuguese Fundacao para a Ciencia e Tecnologia (Project METAGUT; Grant No. ERA-PTG/SAU/0003/2008). |
| WOS记录号 | WOS:000292106500001 |
| 资助机构 | European Union [29104, 222886] ; Ministry of Science and Technology of the People's Republic of China [2011CBA00802] ; Institute of Psychology, Chinese Academy of Sciences [O9CX115011] ; Portuguese Fundacao para a Ciencia e Tecnologia [ERA-PTG/SAU/0003/2008] |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | https://ir.psych.ac.cn/handle/311026/11511 |
| 专题 | 中国科学院心理健康重点实验室 |
| 通讯作者 | dos Santos, VAPM (reprint author), Helmholtz Ctr Infect Res HZI, Syst & Synthet Biol Grp, Inhoffenstr 7, D-38124 Braunschweig, Germany. |
| 作者单位 | 1.Helmholtz Ctr Infect Res HZI, Syst & Synthet Biol Grp, D-38124 Braunschweig, Germany 2.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Beijing 100101, Peoples R China 3.China Agr Univ, Coll Biol Sci, Beijing 100193, Peoples R China 4.Chinese Acad Sci, Grad Univ, Beijing 100101, Peoples R China 5.Lifewizz Lda, P-4150616 Oporto, Portugal 6.Wageningen Univ, NL-6703 HB Wageningen, Netherlands |
| 第一作者单位 | 中国科学院心理健康重点实验室 |
| 推荐引用方式 GB/T 7714 | Fang, Kechi,Zhao, Hansheng,Sun, Changyue,et al. Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction[J]. BMC SYSTEMS BIOLOGY,2011,5. |
| APA | Fang, Kechi.,Zhao, Hansheng.,Sun, Changyue.,Lam, Carolyn M. C..,Chang, Suhua.,...&dos Santos, VAPM .(2011).Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction.BMC SYSTEMS BIOLOGY,5. |
| MLA | Fang, Kechi,et al."Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction".BMC SYSTEMS BIOLOGY 5(2011). |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| WOS_000292106500001.（825KB） | 开放获取 | Apache License | 浏览 下载 | |||
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