PSYCH OpenIR  > 中国科学院心理健康重点实验室
Isolation rearing alters social behaviors and monoamine neurotransmission in the medial prefrontal cortex and nucleus accumbens of adult rats
Han, Xiao2; Wang, Weiwen3; Shao, Feng2; Li, Nanxin1,2; Li, NX (reprint author), Yale Univ, Sch Med, Div Mol Psychiat, Dept Psychol, 34 Pk St, New Haven, CT 06508 USA.
2011-04-18
发表期刊BRAIN RESEARCH
ISSN0006-8993
文章类型Article
卷号1385页码:175-181
产权排序2
摘要Isolation rearing induces profound behavioral and neurochemical abnormalities in rodents. However, there is some controversy regarding the effect of isolation rearing on social behaviors and monoamine neurotransmission in mesolimbic and mesocortical areas. In the current study, we aimed to address these issues and demonstrated that isolation rearing from weaning to adulthood resulted in increased playful fighting and social contact behaviors. Isolation-reared rats also manifested increased dopamine and serotonin levels in the medial prefrontal cortex (mPFC) and nucleus accumbens (NAc) as well as an increase in serotonin turnover in the NAc. This study provides additional evidence that social isolation induces alterations in behavior and in the brain. (C) 2011 Elsevier B.V. All rights reserved.
关键词Aggression Dopamine Isolation rearing Nucleus accumbens Prefrontal cortex Serotonin Social interaction
学科领域Physiological Psychology/biological Psychology
URL查看原文
收录类别SCI
语种英语
项目资助者National Natural Science Foundation of China [31070910] ; National Basic Research Program of China (973 Program) [2007CB512306] ; Chinese Academy of Sciences [KSCX2-YW-R-131] ; American Psychological Association ; Institute of Psychology, Chinese Academy of Science [O9KF013001]
项目简介This work was supported by the National Natural Science Foundation of China (grant No. 31070910), National Basic Research Program of China (973 Program, 2007CB512306), the Chinese Academy of Sciences (KSCX2-YW-R-131), American Psychological Association, and grants to young scientists from the Institute of Psychology, Chinese Academy of Science (O9KF013001).
WOS记录号WOS:000289810800019
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/11879
专题中国科学院心理健康重点实验室
通讯作者Li, NX (reprint author), Yale Univ, Sch Med, Div Mol Psychiat, Dept Psychol, 34 Pk St, New Haven, CT 06508 USA.
作者单位1.Yale Univ, Sch Med, Div Mol Psychiat, Dept Psychol, New Haven, CT 06508 USA
2.Peking Univ, Dept Psychol, Beijing 100871, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
推荐引用方式
GB/T 7714
Han, Xiao,Wang, Weiwen,Shao, Feng,et al. Isolation rearing alters social behaviors and monoamine neurotransmission in the medial prefrontal cortex and nucleus accumbens of adult rats[J]. BRAIN RESEARCH,2011,1385:175-181.
APA Han, Xiao,Wang, Weiwen,Shao, Feng,Li, Nanxin,&Li, NX .(2011).Isolation rearing alters social behaviors and monoamine neurotransmission in the medial prefrontal cortex and nucleus accumbens of adult rats.BRAIN RESEARCH,1385,175-181.
MLA Han, Xiao,et al."Isolation rearing alters social behaviors and monoamine neurotransmission in the medial prefrontal cortex and nucleus accumbens of adult rats".BRAIN RESEARCH 1385(2011):175-181.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
WOS_000289810800019.(426KB) 开放获取Apache License请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Han, Xiao]的文章
[Wang, Weiwen]的文章
[Shao, Feng]的文章
百度学术
百度学术中相似的文章
[Han, Xiao]的文章
[Wang, Weiwen]的文章
[Shao, Feng]的文章
必应学术
必应学术中相似的文章
[Han, Xiao]的文章
[Wang, Weiwen]的文章
[Shao, Feng]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。