PSYCH OpenIR  > 中国科学院心理健康重点实验室
Functional Foveal Splitting: Evidence from Neuropsychological and Multimodal MRI Investigations in a Chinese Patient with a Splenium Lesion
Luo, Benyan1; Shan, Chunlei2; Zhu, Renjing3; Weng, Xuchu4,5; He, Sheng6; Luo, BY (reprint author), Zhejiang Univ, Sch Med, Affiliated Hosp 1, Dept Neurol, Hangzhou 310003, Zhejiang, Peoples R China.
2011-08-26
Source PublicationPLOS ONE
ISSN1932-6203
SubtypeArticle
Volume6Issue:8
Contribution Rank4
AbstractIt remains controversial and hotly debated whether foveal information is double-projected to both hemispheres or split at the midline between the two hemispheres. We investigated this issue in a unique patient with lesions in the splenium of the corpus callosum and the left medial occipitotemporal region, through a series of neuropsychological tests and multimodal MRI scans. Behavioral experiments showed that (1) the patient had difficulties in reading simple and compound Chinese characters when they were presented in the foveal but left to the fixation, (2) he failed to recognize the left component of compound characters when the compound characters were presented in the central foveal field, (3) his judgments of the gender of centrally presented chimeric faces were exclusively based on the left half-face and he was unaware that the faces were chimeric. Functional MRI data showed that Chinese characters, only when presented in the right foveal field but not in the left foveal field, activated a region in the left occipitotemporal sulcus in the mid-fusiform, which is recognized as visual word form area. Together with existing evidence in the literature, results of the current study suggest that the representation of foveal stimuli is functionally split at object processing levels.
Subject AreaMedical Psychology,Cognitive Neuroscience
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Indexed BySCI
Language英语
Funding OrganizationNational Natural Science Foundation [31070905] ; Chinese Ministry of Science and Technology [2007CB512300] ; NSF [BCS-0818588]
Project Intro.This work was supported by 1. National Natural Science Foundation, No. 31070905 (http://www.nsfc.gov.cn/Portal0/default106.htm); 2. Chinese Ministry of Science and Technology, No. 2007CB512300 (http://www.most.gov.cn/eng/); 3. NSF grant BCS-0818588(www.nsf.gov). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
WOS IDWOS:000294298800024
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/12826
Collection中国科学院心理健康重点实验室
Corresponding AuthorLuo, BY (reprint author), Zhejiang Univ, Sch Med, Affiliated Hosp 1, Dept Neurol, Hangzhou 310003, Zhejiang, Peoples R China.
Affiliation1.Zhejiang Univ, Sch Med, Affiliated Hosp 1, Dept Neurol, Hangzhou 310003, Zhejiang, Peoples R China
2.Nanjing Med Univ, Dept Rehabil Med, Affiliated Hosp 1, Nanjing, Peoples R China
3.Xiamen Univ, Zhongshan Hosp, Dept Neurol, Xiamen, Peoples R China
4.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
5.Hangzhou Normal Univ, Ctr Human Brain Res, Hangzhou, Zhejiang, Peoples R China
6.Univ Minnesota, Dept Psychol, Minneapolis, MN 55455 USA
Recommended Citation
GB/T 7714
Luo, Benyan,Shan, Chunlei,Zhu, Renjing,et al. Functional Foveal Splitting: Evidence from Neuropsychological and Multimodal MRI Investigations in a Chinese Patient with a Splenium Lesion[J]. PLOS ONE,2011,6(8).
APA Luo, Benyan,Shan, Chunlei,Zhu, Renjing,Weng, Xuchu,He, Sheng,&Luo, BY .(2011).Functional Foveal Splitting: Evidence from Neuropsychological and Multimodal MRI Investigations in a Chinese Patient with a Splenium Lesion.PLOS ONE,6(8).
MLA Luo, Benyan,et al."Functional Foveal Splitting: Evidence from Neuropsychological and Multimodal MRI Investigations in a Chinese Patient with a Splenium Lesion".PLOS ONE 6.8(2011).
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