PSYCH OpenIR  > 中国科学院心理健康重点实验室
Moxibustion Attenuates Inflammatory Response to Chronic Exhaustive Exercise in Rats
Lu, J.2; Zhang, H. -L.2; Yin, Z. -Z.2; Tu, Y.2; Li, Z. -G.2; Zhao, B. -X.2; Guo, J. -Y.1; Guo, JY (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, 4A Datun Rd, Beijing 100101, Peoples R China.
2012-07-01
发表期刊INTERNATIONAL JOURNAL OF SPORTS MEDICINE
ISSN0172-4622
文章类型Article
卷号33期号:7页码:580-585
产权排序2
摘要Exercise is recognized as an activator to elicit an inflammatory response whilst moxibustion in traditional Chinese medicine has been previously found to modulate immune functioning. However, whether moxibustion can alleviate the inflammatory cytokines response to chronic exhaustive exercise remains unknown. In the present study, rats were randomly assigned to a sedentary control group (Sed), a sedentary moxibustion group (Sed + Moxa), and 2 trained groups- one submitted to a 3-week exhaustive swimming (Trained), and the other a trained moxibustion group (Trained + Moxa). We found that chronic exhaustive exercise significantly increased the serum levels of pro-inflammatory cytokines (IL-1 beta, TNF-alpha, IFN-gamma) and the IFN-gamma/IL-4 ratio, and decreased the anti-inflammatory cytokines (IL-4, IL-10). Moxibustion treatment markedly reduced the serum levels of IL-1 beta, IFN-gamma and the IFN-gamma/IL-4 ratio, while elevated the IL-4 and IL-10 productions in trained rats. However, TNF-alpha level was not significantly affected. Our results suggested that an excessive inflammatory response and a potential inflammatory damage may be involved during chronic exhaustive exercise. Moxibustion could attenuate the inflammatory impairment and have an anti-inflammatory effect. The beneficial effects of moxibustion might be mediated by reducing the pro-inflammatory cytokines, increasing the anti-inflammatory cytokines, and modulating the balance between pro- and anti-inflammatory cytokines.
关键词exhaustive exercise cytokines inflammation moxibustion T helper
学科领域Sports Psychology
收录类别SCI
语种英语
项目资助者Beijing University of Chinese Medicine [2008X-094] ; National Basic Research Program of China (973 program) [2009CB522906] ; NNSF [30800301, 31170992, 81102638] ; Ministry of Science and Technology [2010ZX09102-201-018] ; Chinese Academy of Sciences [KSCX2-YW-R-254, KSCX2-EW-Q-18, KSCX2-EW-J-8] ; Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences
项目简介We thank Dr. Michele Audrey Ball for her advice on the manuscript. This study was supported in part by the grants from Beijing University of Chinese Medicine (No. 2008X-094) and National Basic Research Program of China (973 program, No. 2009CB522906), NNSF grant (30800301, 31170992, 81102638), the Key New Drugs Innovation project from Ministry of Science and Technology (2010ZX09102-201-018), the Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-YW-R-254, KSCX2-EW-Q-18 and KSCX2-EW-J-8) and Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.
WOS记录号WOS:000306105600014
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/12861
专题中国科学院心理健康重点实验室
通讯作者Guo, JY (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, 4A Datun Rd, Beijing 100101, Peoples R China.
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
2.Beijing Univ Chinese Med, Coll Acupuncture Moxibust & Tui Na, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Lu, J.,Zhang, H. -L.,Yin, Z. -Z.,et al. Moxibustion Attenuates Inflammatory Response to Chronic Exhaustive Exercise in Rats[J]. INTERNATIONAL JOURNAL OF SPORTS MEDICINE,2012,33(7):580-585.
APA Lu, J..,Zhang, H. -L..,Yin, Z. -Z..,Tu, Y..,Li, Z. -G..,...&Guo, JY .(2012).Moxibustion Attenuates Inflammatory Response to Chronic Exhaustive Exercise in Rats.INTERNATIONAL JOURNAL OF SPORTS MEDICINE,33(7),580-585.
MLA Lu, J.,et al."Moxibustion Attenuates Inflammatory Response to Chronic Exhaustive Exercise in Rats".INTERNATIONAL JOURNAL OF SPORTS MEDICINE 33.7(2012):580-585.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
WOS000306105600014.p(467KB) 限制开放Apache License浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Lu, J.]的文章
[Zhang, H. -L.]的文章
[Yin, Z. -Z.]的文章
百度学术
百度学术中相似的文章
[Lu, J.]的文章
[Zhang, H. -L.]的文章
[Yin, Z. -Z.]的文章
必应学术
必应学术中相似的文章
[Lu, J.]的文章
[Zhang, H. -L.]的文章
[Yin, Z. -Z.]的文章
相关权益政策
暂无数据
收藏/分享
文件名: WOS000306105600014.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。