Institutional Repository of Key Laboratory of Mental Health, CAS
Multilocus association mapping using generalized ridge logistic regression | |
Liu, Zhe2; Shen, Yuanyuan3; Ott, Jurg1; Ott, J (reprint author), Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, 4A Datun Rd, Beijing 100101, Peoples R China. | |
心理所单位排序 | 3 |
摘要 | Background: In genome-wide association studies, it is widely accepted that multilocus methods are more powerful than testing single-nucleotide polymorphisms (SNPs) one at a time. Among statistical approaches considering many predictors simultaneously, scan statistics are an effective tool for detecting susceptibility genomic regions and mapping disease genes. In this study, inspired by the idea of scan statistics, we propose a novel sliding window-based method for identifying a parsimonious subset of contiguous SNPs that best predict disease status. |
学科领域 | Physiological Psychology/biological Psychology |
2011-09-29 | |
语种 | 英语 |
发表期刊 | BMC BIOINFORMATICS
![]() |
ISSN | 1471-2105 |
卷号 | 12 |
期刊论文类型 | Article |
URL | 查看原文 |
收录类别 | SCI |
项目简介 | This work has been supported by NSFC grants from the Chinese government (project numbers 30730057 and 30700442) to JO. |
WOS记录号 | WOS:000295848700001 |
资助机构 | NSFC from the Chinese government [30730057, 30700442] |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/12862 |
专题 | 中国科学院心理健康重点实验室 |
通讯作者 | Ott, J (reprint author), Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, 4A Datun Rd, Beijing 100101, Peoples R China. |
作者单位 | 1.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Beijing 100101, Peoples R China 2.Univ Chicago, Dept Stat, Chicago, IL 60637 USA 3.Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA |
推荐引用方式 GB/T 7714 | Liu, Zhe,Shen, Yuanyuan,Ott, Jurg,et al. Multilocus association mapping using generalized ridge logistic regression[J]. BMC BIOINFORMATICS,2011,12. |
APA | Liu, Zhe,Shen, Yuanyuan,Ott, Jurg,&Ott, J .(2011).Multilocus association mapping using generalized ridge logistic regression.BMC BIOINFORMATICS,12. |
MLA | Liu, Zhe,et al."Multilocus association mapping using generalized ridge logistic regression".BMC BIOINFORMATICS 12(2011). |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
WOS_000295848700001.(303KB) | 限制开放 | Apache License | 请求全文 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论