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| Protection by Vanadium, a Contemporary Treatment Approach to Both Diabetes and Focal Cerebral Ischemia in Rats | |
Liu, Zhenquan2; Li, Pengtao2; Zhao, Dan2; Tang, Huiling2; Guo, Jianyou1 ; Guo, JY (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
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| 心理所单位排序 | 2 |
| 摘要 | There is now substantial epidemiological evidence that diabetes is a risk factor for cerebrovascular disease. The protection by vanadium from focal cerebral ischemia in diabetic rats was studied in this paper. Rats with streptozotocin-induced diabetes were subjected to middle cerebral artery occlusion followed by 4 weeks of administration of 0.6 mg/ml sodium orthovanadate in drinking water. Vanadium significantly improved the outcome in diabetic rats after cerebral ischemia and reperfusion in terms of neurobehavioral function. Vanadium reduces brain damage in streptozotocin-induced diabetic rats by imitating action of insulin. |
| 关键词 | Vanadium Diabetes Focal cerebral ischemia Insulin Cerebrovascular disease |
| 学科领域 | Medical Psychology |
| 2012 | |
| 语种 | 英语 |
| 发表期刊 | BIOLOGICAL TRACE ELEMENT RESEARCH
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| ISSN | 0163-4984 |
| 卷号 | 145期号:1页码:66-70 |
| 期刊论文类型 | Article |
| URL | 查看原文 |
| 收录类别 | SCI |
| 项目简介 | This work was supported by the Key New Drugs Innovation project from Ministry of Science and Technology (2009ZX09502-017), Program for New Century Excellent Talents in University (NCET-10-0273), Beijing Nova Program (2010B035), the project from Key Laboratory of Mental Health, Chinese Academy of Sciences, Young Scientist project from IPCAS (08CX043004), NNSF grant (30800301), and the Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-YW-R-254, KSCX2-EW-Q-18 and KSCX2-EW-J-8). |
| WOS记录号 | WOS:000299090300009 |
| 资助机构 | Ministry of Science and Technology [2009ZX09502-017] ; Program for New Century Excellent Talents in University [NCET-10-0273] ; Beijing Nova Program [2010B035] ; Key Laboratory of Mental Health ; Chinese Academy of Sciences [KSCX2-YW-R-254, KSCX2-EW-Q-18, KSCX2-EW-J-8] ; IPCAS [08CX043004] ; NNSF [30800301] |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.psych.ac.cn/handle/311026/12906 |
| 专题 | 中国科学院心理健康重点实验室 |
| 通讯作者 | Guo, JY (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China. |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Beijing Univ Chinese Med, Sch Basic Med Sci, Beijing 100102, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Zhenquan,Li, Pengtao,Zhao, Dan,et al. Protection by Vanadium, a Contemporary Treatment Approach to Both Diabetes and Focal Cerebral Ischemia in Rats[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2012,145(1):66-70. |
| APA | Liu, Zhenquan,Li, Pengtao,Zhao, Dan,Tang, Huiling,Guo, Jianyou,&Guo, JY .(2012).Protection by Vanadium, a Contemporary Treatment Approach to Both Diabetes and Focal Cerebral Ischemia in Rats.BIOLOGICAL TRACE ELEMENT RESEARCH,145(1),66-70. |
| MLA | Liu, Zhenquan,et al."Protection by Vanadium, a Contemporary Treatment Approach to Both Diabetes and Focal Cerebral Ischemia in Rats".BIOLOGICAL TRACE ELEMENT RESEARCH 145.1(2012):66-70. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| WOS_000299090300009.（151KB） | 限制开放 | Apache License | 请求全文 | |||
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