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Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up
Yin, Jianzhong1; Xue, Yonggang1; Lin, Peng2; Weng, Xuchu3; Qi, Ji1; Yin, JZ (reprint author), Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Radiol, Tianjin 300192, Peoples R China.
2011-04-15
Source PublicationNEURAL REGENERATION RESEARCH
ISSN1673-5374
SubtypeArticle
Volume6Issue:11Pages:834-838
Contribution Rank3
AbstractDuring speech restoration following laryngectomy, language-related cortical areas develop connections with new primary motor neurons. The present study followed up 18 patients after total resection of laryngeal carcinoma. According to an evaluation of pronunciation, patients were assigned to three groups: poor, moderate and good pronunciation. Functional magnetic resonance imaging revealed significant increases in the number of activated voxels and the intensity of activation changes in the left middle frontal gyrus, left precentral gyrus, left postcentral gyrus, left supplementary motor area, left anterior cingulate gyrus and right fusiform gyrus between the moderate pronunciation group compared with the poor and good pronunciation groups. We propose that these brain regions play an important role in the progress of speech restoration, and improvements in pronunciation learning for patients following laryngectomy. However, during the later period of speech restoration, the number of activated voxels and intensity changes in these regions decreased to the level of healthy controls, indicating that the learning and instruction effects weakened once patients had mastered pronunciation techniques.
Keywordmagnetic resonance imaging functional laryngeal carcinoma laryngectomy language training neuroplasticity
Subject AreaMedical Psychology
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Indexed BySCI
Language英语
Funding OrganizationNatural Science Foundation of Tianjin [06YFJMJC09300]
Project Intro.The study was supported by the Natural Science Foundation of Tianjin, No. 06YFJMJC09300.
WOS IDWOS:000291416100007
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/13241
Collection中国科学院心理健康重点实验室
Corresponding AuthorYin, JZ (reprint author), Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Radiol, Tianjin 300192, Peoples R China.
Affiliation1.Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Radiol, Tianjin 300192, Peoples R China
2.Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Otolaryngol, Tianjin 300192, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China
Recommended Citation
GB/T 7714
Yin, Jianzhong,Xue, Yonggang,Lin, Peng,et al. Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up[J]. NEURAL REGENERATION RESEARCH,2011,6(11):834-838.
APA Yin, Jianzhong,Xue, Yonggang,Lin, Peng,Weng, Xuchu,Qi, Ji,&Yin, JZ .(2011).Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up.NEURAL REGENERATION RESEARCH,6(11),834-838.
MLA Yin, Jianzhong,et al."Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up".NEURAL REGENERATION RESEARCH 6.11(2011):834-838.
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