Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array

	Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array
	Yang, Liu 2,3; Zhang, Kunlin1 ; Dai, Wei 2; He, Ximiao 1; Zhao, Qian 1; Wang, Jing1 ; Sun, Zhong Sheng 2; Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
心理所单位排序	1,2
摘要	Background: Recent progress in high-throughput technologies has greatly contributed to the development of DNA methylation profiling. Although there are several reports that describe methylome detection of whole genome bisulfite sequencing, the high cost and heavy demand on bioinformatics analysis prevents its extensive application. Thus, current strategies for the study of mammalian DNA methylomes is still based primarily on genome-wide methylated DNA enrichment combined with DNA microarray detection or sequencing. Methylated DNA enrichment is a key step in a microarray based genome-wide methylation profiling study, and even for future high-throughput sequencing based methylome analysis.
学科领域	Physiological Psychology/biological Psychology
	2011-01-06
语种	英语
发表期刊	BMC GENOMICS
ISSN	1471-2164
卷号	12
期刊论文类型	Article
URL	查看原文
收录类别	SCI
项目简介	This work was sponsored by the National High Technology Research and Development Program of China (863 Program) (Grant No. 2006AA02A304, to ZSS) from the Ministry of Science and Technology of the People's Republic of China; the National Natural Science Foundation of China (NSFC) (Grant No. 30221004, to ZSS); the Innovation Project of Chinese Academy of Sciences (KSCX2-YW-R-38, to ZSS); and Project for Young Scientists Fund, Institute of Psychology, Chinese Academy of Sciences (O9CX115011, to KZ). Funding to pay the Open Access publication charges for this article was also provided by the 863 grant. We thank Dr Laurie Goodman for her helpful suggestions to help us refine the manuscript. We also thank all staffs at Institute of Psychology, Chinese Academy of Sciences, for their sincere supports. We thank the anonymous reviewers for kind comments.
WOS记录号	WOS:000286425600001
资助机构	Ministry of Science and Technology of the People's Republic of China [2006AA02A304] ; National Natural Science Foundation of China (NSFC) [30221004] ; Chinese Academy of Sciences [KSCX2-YW-R-38] ; Institute of Psychology, Chinese Academy of Sciences [O9CX115011] ; 863 grant
引用统计	被引频次：10[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/13275
专题	中国科学院心理健康重点实验室
通讯作者	Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Behav Genet Ctr, Beijing 100101, Peoples R China 3.Zhejiang Univ, Sch Med, Hangzhou 310058, Zhejiang, Peoples R China
第一作者单位	健康与遗传心理学研究室
推荐引用方式 GB/T 7714	Yang, Liu,Zhang, Kunlin,Dai, Wei,et al. Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array[J]. BMC GENOMICS,2011,12.
APA	Yang, Liu.,Zhang, Kunlin.,Dai, Wei.,He, Ximiao.,Zhao, Qian.,...&Wang, J .(2011).Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array.BMC GENOMICS,12.
MLA	Yang, Liu,et al."Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array".BMC GENOMICS 12(2011).

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