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Translating genomic research into care for people with schizophrenia in China
Chan, Raymond C. K.1; Austin, Jehannine C.2,3,4; Pearson, Veronica J.5; Gong, Qi-Yong6; Honer, William G.2,3; Chan, RCK (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, 4A Datun Rd, Beijing 100101, Peoples R China.
2011-09-01
Source PublicationSCHIZOPHRENIA RESEARCH
ISSN0920-9964
SubtypeArticle
Volume131Issue:1-3Pages:31-34
Contribution Rank1
AbstractThe implications of increased understanding of the genetic contribution to schizophrenia for patients and their families remain unclear. We carried out a study of Chinese patients'(n = 118) and relatives' (n = 78) views of illness severity, attribution of cause, concern about developing illness, and effect of schizophrenia on family planning. A comparison sample of English-survey respondents was also obtained, using the same series of questions (n = 42 patients, n = 127 relatives). Fewer Chinese patients and family members rated schizophrenia as very severe (33%) than did the predominantly North American respondents (67%, p<0.0001). The pattern of attribution of cause differed between samples (p<0.0001), favoring environmental alone in the Chinese sample (52%), with a low frequency of genetics alone (9%). Although comparatively fewer Chinese respondents were very concerned about developing schizophrenia themselves or about the risk of illness in their families (21%), this high level of concern was more common in family members (28%). Finally, Chinese respondents were somewhat less likely to indicate that schizophrenia impacted on family planning decisions (31%) than were English-survey respondents (45%, p = 0.02). The descriptive findings contribute to understanding schizophrenia in China. The comparative findings must be regarded as preliminary, since differences in demographics could influence results. The present findings suggest that understanding patients' and families' attributions of cause of schizophrenia may be important for developing a shared model of illness in order to decrease stigmatization, and improve therapeutic alliances. (C) 2011 Elsevier B.V. All rights reserved.
KeywordSchizophrenia Genetics Stigma Causal attributions
Subject AreaAbnormal Psychology
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Indexed BySCI ; SSCI
Language英语
Funding OrganizationKey Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences [O7CX031003] ; Chinese Academy of Sciences [KSCX2-YW-R-131, KSCX2-EW-J-8] ; National Basic Research Programme (973 Programme) [2007CB512302/5] ; National Science Foundation China [81088001] ; Canadian Institutes of Health Research [NET-54013] ; Michael Smith Foundation for Health Research ; BC Mental Health and Addictions Services
Project Intro.The project was funded by: the Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Project-Oriented Hundred Talents Programme (O7CX031003), the Knowledge Innovation Project of the Chinese Academy of Sciences (KSCX2-YW-R-131 and KSCX2-EW-J-8), a grant from the National Basic Research Programme (973 Programme No. 2007CB512302/5), and an Outstanding National Young Investigator Award from the National Science Foundation China (81088001) to RCK Chan. Funding for the Canadian component was from the Canadian Institutes of Health Research (NET-54013), Michael Smith Foundation for Health Research, and the BC Mental Health and Addictions Services. None of the funding agencies had any influence over the data collection, analysis or preparation of the manuscript.
WOS IDWOS:000295111400006
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Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/13322
Collection脑与认知科学国家重点实验室
Corresponding AuthorChan, RCK (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, 4A Datun Rd, Beijing 100101, Peoples R China.
Affiliation1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
2.Univ British Columbia, BC Mental Hlth & Addict Res Inst, Vancouver, BC V5Z 1M9, Canada
3.Univ British Columbia, Dept Psychiat, Vancouver, BC, Canada
4.Univ British Columbia, Dept Med Genet, Vancouver, BC, Canada
5.Univ Hong Kong, Dept Social Work & Social Adm, Hong Kong, Hong Kong, Peoples R China
6.Sichuan Univ, Huaxi MR Res Ctr, Dept Radiol, W China Hosp,W China Sch Med, Chengdu 610064, Peoples R China
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GB/T 7714
Chan, Raymond C. K.,Austin, Jehannine C.,Pearson, Veronica J.,et al. Translating genomic research into care for people with schizophrenia in China[J]. SCHIZOPHRENIA RESEARCH,2011,131(1-3):31-34.
APA Chan, Raymond C. K.,Austin, Jehannine C.,Pearson, Veronica J.,Gong, Qi-Yong,Honer, William G.,&Chan, RCK .(2011).Translating genomic research into care for people with schizophrenia in China.SCHIZOPHRENIA RESEARCH,131(1-3),31-34.
MLA Chan, Raymond C. K.,et al."Translating genomic research into care for people with schizophrenia in China".SCHIZOPHRENIA RESEARCH 131.1-3(2011):31-34.
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