Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time

	Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time
	Chan, Raymond C. K.1 ; Dai, Shan 2; Lui, Simon S. Y.1,3,4; Ho, Karen K. Y.3; Hung, Karen S. Y.3; Wang, Ya1 ; Geng, Fu-lei 1,3; Li, Zhi 1,3; Cheung, Eric F. C.4
Abstract	The present study examined different types of neurological signs in patients with first-episode schizophrenia and their relationships with neurocognitive functions. Both cross-sectional and longitudinal designs were adopted with the use of the abridged Cambridge Neurological Inventory which comprises items capturing motor coordination, sensory integration and disinhibition. A total of 157 patients with first-episode schizophrenia were assessed at baseline and 101 of them were re-assessed at six-month interval. A structural equation model (SEM) with invariance model across time was used for data analysis. The model fitted well with the data at baseline assessment, X<^>2(21) = 21.78, p = 0.413, NFI = 0.95, NNFI = 1.00, CFI = 1.00, IFI = 1.00, RMSEA = 0.015. Subsequent SEM analysis with invariance model at six-month interval also demonstrated the same stable pattern across time and showed strong measurement invariance and structure invariance across time. Our findings suggest that neurological signs capture more or less the same construct captured by conventional neurocognitive tests in patients with schizophrenia. The measurement and structure of these relationships appear to be stable over time.
	2015-07-02
Language	英语
Source Publication	SCIENTIFIC REPORTS
ISSN	2045-2322
Volume	5 Issue:0 Pages:11850
Subtype	Article
Indexed By	SCI ; SSCI
WOS ID	WOS:000357269100001
Citation statistics	Cited Times:6[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.psych.ac.cn/handle/311026/13341
Collection	中国科学院心理健康重点实验室
Affiliation	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China 2.Univ Sci & Technol China, Dept Stat & Finance, Hefei 230026, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
First Author Affilication	认知与发展心理学研究室
Recommended Citation GB/T 7714	Chan, Raymond C. K.,Dai, Shan,Lui, Simon S. Y.,et al. Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time[J]. SCIENTIFIC REPORTS,2015,5(0):11850.
APA	Chan, Raymond C. K..,Dai, Shan.,Lui, Simon S. Y..,Ho, Karen K. Y..,Hung, Karen S. Y..,...&Cheung, Eric F. C..(2015).Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time.SCIENTIFIC REPORTS,5(0),11850.
MLA	Chan, Raymond C. K.,et al."Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time".SCIENTIFIC REPORTS 5.0(2015):11850.

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