Dimensional schizotypy and social cognition: an fMRI imaging study

	Dimensional schizotypy and social cognition: an fMRI imaging study
	Wang, Yi1 ; Liu, Wen-hua 2; Li, Zhi 1,3; Wei, Xin-hua 4; Jiang, Xin-qing 4; Neumann, David L.5,6; Shum, David H. K.5,6; Cheung, Eric F. C.7; Chan, Raymond C. K.1
摘要	Impairment in empathy has been demonstrated in patients with schizophrenia and individuals with psychosis proneness. In the present study, we examined the neural correlates underlying theory of mind (ToM) and empathy and the relationships between these two social cognitive abilities with schizotypy. Fifty-six first-year college students (31 males, 25 females) between 17 and 21 years of age (M = 19.3, SD = 0.9) from a medical university in China participated. All participants undertook a comic strips functional imaging task that specifically examined both empathy and ToM. In addition, they completed two self-report scales: the Chapman Psychosis Proneness scale and the Interpersonal Responsivity Index (IRI). Results showed that both empathy and ToM conditions of the task were associated with brain activity in the middle temporal gyrus, the temporo-parietal junction (TPJ), the precuneus and the posterior cingulate gyrus. In addition, we found positive correlations between negative schizotypy and brain activity in regions involved in social cognition, namely, the middle temporal gyrus, the TPJ, as well as the medial prefrontal gyrus. These findings highlight that different dimensions of schizotypy may show different associations with brain regions involved in social cognitive abilities. More importantly, the positive correlation between brain activity and anhedonia suggests the presence of compensatory mechanisms in high-risk populations.
关键词	schizotypy theory of mind empathy fMRI anhedonia
	2015-05-27
语种	英语
发表期刊	FRONTIERS IN BEHAVIORAL NEUROSCIENCE
ISSN	1662-5153
卷号	9 期号:0 页码:133
期刊论文类型	Article
收录类别	SCI
WOS记录号	WOS:000356781500001
引用统计	被引频次：35[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.psych.ac.cn/handle/311026/13350
专题	中国科学院心理健康重点实验室
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 10101, Peoples R China 2.Guangzhou Med Univ, Sch Hlth Management, Guangzhou, Guangdong, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Guangzhou First Peoples Hosp, Dept Radiol, Guangzhou, Guangdong, Peoples R China 5.Griffith Univ, Menzies Hlth Inst Queensland, Gold Coast, Qld, Australia 6.Griffith Univ, Sch Appl Psychol, Gold Coast, Qld, Australia 7.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yi,Liu, Wen-hua,Li, Zhi,et al. Dimensional schizotypy and social cognition: an fMRI imaging study[J]. FRONTIERS IN BEHAVIORAL NEUROSCIENCE,2015,9(0):133.
APA	Wang, Yi.,Liu, Wen-hua.,Li, Zhi.,Wei, Xin-hua.,Jiang, Xin-qing.,...&Chan, Raymond C. K..(2015).Dimensional schizotypy and social cognition: an fMRI imaging study.FRONTIERS IN BEHAVIORAL NEUROSCIENCE,9(0),133.
MLA	Wang, Yi,et al."Dimensional schizotypy and social cognition: an fMRI imaging study".FRONTIERS IN BEHAVIORAL NEUROSCIENCE 9.0(2015):133.

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