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Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis | |
Juyal, Garima1; Negi, Sapna2; Sood, Ajit3; Gupta, Aditi1; Prasad, Pushplata1; Senapati, Sabyasachi1; Zaneveld, Jacques4; Singh, Shalini1; Midha, Vandana3; van Sommeren, Suzanne5; Weersma, Rinse K.5; Ott, Jurg6; Jain, Sanjay7,8; Juyal, Ramesh C.2; Thelma, B. K.1 | |
摘要 | Objective Over 100 ulcerative colitis (UC) loci have been identified by genome-wide association studies (GWASs) primarily in Caucasians (CEUs). Many of them have weak effects on disease susceptibility, and the bulk of the heritability cannot be ascribed to these loci. Very little is known about the genetic background of UC in non-CEU groups. Here we report the first GWAS on UC in a genetically distinct north Indian (NI) population. |
2015-04-01 | |
语种 | 英语 |
发表期刊 | GUT
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ISSN | 0017-5749 |
卷号 | 64期号:4页码:571-579 |
期刊论文类型 | Article |
收录类别 | SCI |
WOS记录号 | WOS:000350800100010 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://ir.psych.ac.cn/handle/311026/13412 |
专题 | 中国科学院心理健康重点实验室 |
作者单位 | 1.Univ Delhi, Dept Genet, New Delhi 110021, India 2.Natl Inst Immunol, New Delhi 110067, India 3.Dayanand Med Coll & Hosp, Dept Gastroenterol, Ludhiana, Punjab, India 4.Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA 5.Univ Groningen, Univ Med Ctr Groningen, Dept Gastroenterol, Groningen, Netherlands 6.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 7.Univ Delhi, Dept Phys, Delhi 110007, India 8.Univ Delhi, Dept Astrophys, Delhi 110007, India |
推荐引用方式 GB/T 7714 | Juyal, Garima,Negi, Sapna,Sood, Ajit,et al. Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis[J]. GUT,2015,64(4):571-579. |
APA | Juyal, Garima.,Negi, Sapna.,Sood, Ajit.,Gupta, Aditi.,Prasad, Pushplata.,...&Thelma, B. K..(2015).Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis.GUT,64(4),571-579. |
MLA | Juyal, Garima,et al."Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis".GUT 64.4(2015):571-579. |
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Genome-wide associat(4078KB) | 期刊论文 | 作者接受稿 | 暂不开放 | CC BY-NC-SA | 请求全文 |
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