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Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis
Juyal, Garima1; Negi, Sapna2; Sood, Ajit3; Gupta, Aditi1; Prasad, Pushplata1; Senapati, Sabyasachi1; Zaneveld, Jacques4; Singh, Shalini1; Midha, Vandana3; van Sommeren, Suzanne5; Weersma, Rinse K.5; Ott, Jurg6; Jain, Sanjay7,8; Juyal, Ramesh C.2; Thelma, B. K.1
2015-04-01
发表期刊GUT
ISSN0017-5749
文章类型Article
卷号64期号:4页码:571-579
摘要Objective Over 100 ulcerative colitis (UC) loci have been identified by genome-wide association studies (GWASs) primarily in Caucasians (CEUs). Many of them have weak effects on disease susceptibility, and the bulk of the heritability cannot be ascribed to these loci. Very little is known about the genetic background of UC in non-CEU groups. Here we report the first GWAS on UC in a genetically distinct north Indian (NI) population.
收录类别SCI
语种英语
WOS记录号WOS:000350800100010
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文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/13412
专题中国科学院心理健康重点实验室
作者单位1.Univ Delhi, Dept Genet, New Delhi 110021, India
2.Natl Inst Immunol, New Delhi 110067, India
3.Dayanand Med Coll & Hosp, Dept Gastroenterol, Ludhiana, Punjab, India
4.Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA
5.Univ Groningen, Univ Med Ctr Groningen, Dept Gastroenterol, Groningen, Netherlands
6.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
7.Univ Delhi, Dept Phys, Delhi 110007, India
8.Univ Delhi, Dept Astrophys, Delhi 110007, India
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Juyal, Garima,Negi, Sapna,Sood, Ajit,et al. Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis[J]. GUT,2015,64(4):571-579.
APA Juyal, Garima.,Negi, Sapna.,Sood, Ajit.,Gupta, Aditi.,Prasad, Pushplata.,...&Thelma, B. K..(2015).Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis.GUT,64(4),571-579.
MLA Juyal, Garima,et al."Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis".GUT 64.4(2015):571-579.
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