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Support Vector Machines with L-1 penalty for detecting gene-gene interactions | |
Shen, Yuanyuan2; Liu, Zhe3; Ott, Jurg1 | |
摘要 | Interactions among genetic variants are likely to affect risk for human complex diseases, and their identification should increase the power to detect disease-associated variants and elucidate biological pathways underlying diseases. We propose a two-stage approach: |
关键词 | genome-wide association study human complex disease gene-gene interaction SVM support vector machine model selection L-1 penalty two-stage method data mining bioinformatics |
2012 | |
语种 | 英语 |
发表期刊 | INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS |
ISSN | 1748-5673 |
卷号 | 6期号:5页码:463-470 |
期刊论文类型 | Article |
收录类别 | SCI |
WOS记录号 | WOS:000309610700001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/13423 |
专题 | 中国科学院心理健康重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA 3.Univ Chicago, Dept Stat, Chicago, IL 60637 USA |
推荐引用方式 GB/T 7714 | Shen, Yuanyuan,Liu, Zhe,Ott, Jurg. Support Vector Machines with L-1 penalty for detecting gene-gene interactions[J]. INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS,2012,6(5):463-470. |
APA | Shen, Yuanyuan,Liu, Zhe,&Ott, Jurg.(2012).Support Vector Machines with L-1 penalty for detecting gene-gene interactions.INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS,6(5),463-470. |
MLA | Shen, Yuanyuan,et al."Support Vector Machines with L-1 penalty for detecting gene-gene interactions".INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS 6.5(2012):463-470. |
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