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Homotopic connectivity in drug-naive, first-episode, early-onset schizophrenia
Li, Hui-Jie1,2,3; Xu, Yong4; Zhang, Ke-Rang4; Hoptman, Matthew J.5,6; Zuo, Xi-Nian1,2,3
第一作者Li, Hui-Jie
通讯作者邮箱zuoxn@psych.ac.cn
心理所单位排序1
摘要

BackgroundThe disconnection hypothesis of schizophrenia has been extensively tested in adults. Recent studies have reported the presence of brain disconnection in younger patients, adding evidence to support the neurodevelopmental hypothesis of schizophrenia. Because of drug confounds in chronic and medicated patients, it has been extremely challenging for researchers to directly investigate abnormalities in the development of connectivity and their role in the pathophysiology of schizophrenia. The present study aimed to examine functional homotopy - a measure of interhemispheric connection - and its relevance to clinical symptoms in first-episode drug-naive early-onset schizophrenia (EOS) patients.

关键词Resting-state fMRI early-onset schizophrenia functional connectivity interhemispheric connectivity
2015-04-01
语种英语
发表期刊JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
ISSN0021-9630
卷号56期号:4页码:432-443
期刊论文类型Article
收录类别SSCI ; SSCI
WOS记录号WOS:000351402400005
Q分类Q1
引用统计
被引频次:55[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/13500
专题中国科学院行为科学重点实验室
通讯作者Zuo, Xi-Nian
作者单位1.Chinese Acad Sci, Key Lab Behav Sci, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Lab Funct Connectome & Dev, Beijing 100101, Peoples R China
4.Shanxi Med Univ, Hosp 1, Dept Psychiat, Taiyuan, Peoples R China
5.NYU, Sch Med, Dept Psychiat, New York, NY USA
6.Nathan S Kline Inst Psychiat Res, Schizophrenia Res Div, Orangeburg, NY 10962 USA
第一作者单位中国科学院行为科学重点实验室;  管理支撑系统;  认知与发展心理学研究室
通讯作者单位中国科学院行为科学重点实验室;  管理支撑系统;  认知与发展心理学研究室
推荐引用方式
GB/T 7714
Li, Hui-Jie,Xu, Yong,Zhang, Ke-Rang,et al. Homotopic connectivity in drug-naive, first-episode, early-onset schizophrenia[J]. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY,2015,56(4):432-443.
APA Li, Hui-Jie,Xu, Yong,Zhang, Ke-Rang,Hoptman, Matthew J.,&Zuo, Xi-Nian.(2015).Homotopic connectivity in drug-naive, first-episode, early-onset schizophrenia.JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY,56(4),432-443.
MLA Li, Hui-Jie,et al."Homotopic connectivity in drug-naive, first-episode, early-onset schizophrenia".JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY 56.4(2015):432-443.
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