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Homotopic connectivity in drug-naive, first-episode, early-onset schizophrenia
Li, Hui-Jie1,2,3; Xu, Yong4; Zhang, Ke-Rang4; Hoptman, Matthew J.5,6; Zuo, Xi-Nian1,2,3
2015-04-01
发表期刊JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
ISSN0021-9630
文章类型Article
卷号56期号:4页码:432-443
摘要BackgroundThe disconnection hypothesis of schizophrenia has been extensively tested in adults. Recent studies have reported the presence of brain disconnection in younger patients, adding evidence to support the neurodevelopmental hypothesis of schizophrenia. Because of drug confounds in chronic and medicated patients, it has been extremely challenging for researchers to directly investigate abnormalities in the development of connectivity and their role in the pathophysiology of schizophrenia. The present study aimed to examine functional homotopy - a measure of interhemispheric connection - and its relevance to clinical symptoms in first-episode drug-naive early-onset schizophrenia (EOS) patients.
关键词Resting-state fMRI early-onset schizophrenia functional connectivity interhemispheric connectivity
收录类别SSCI
语种英语
WOS记录号WOS:000351402400005
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/13500
专题中国科学院行为科学重点实验室
作者单位1.Chinese Acad Sci, Key Lab Behav Sci, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Lab Funct Connectome & Dev, Beijing 100101, Peoples R China
4.Shanxi Med Univ, Hosp 1, Dept Psychiat, Taiyuan, Peoples R China
5.NYU, Sch Med, Dept Psychiat, New York, NY USA
6.Nathan S Kline Inst Psychiat Res, Schizophrenia Res Div, Orangeburg, NY 10962 USA
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GB/T 7714
Li, Hui-Jie,Xu, Yong,Zhang, Ke-Rang,et al. Homotopic connectivity in drug-naive, first-episode, early-onset schizophrenia[J]. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY,2015,56(4):432-443.
APA Li, Hui-Jie,Xu, Yong,Zhang, Ke-Rang,Hoptman, Matthew J.,&Zuo, Xi-Nian.(2015).Homotopic connectivity in drug-naive, first-episode, early-onset schizophrenia.JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY,56(4),432-443.
MLA Li, Hui-Jie,et al."Homotopic connectivity in drug-naive, first-episode, early-onset schizophrenia".JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY 56.4(2015):432-443.
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