PSYCH OpenIR  > 中国科学院行为科学重点实验室
Prefrontal cortex and the dysconnectivity hypothesis of schizophrenia
Zhou, Yuan1,2; Fan, Lingzhong3,4; Qiu, Chenxiang3,4; Jiang, Tianzi3,4,5,6
2015-04-01
发表期刊NEUROSCIENCE BULLETIN
ISSN1673-7067
文章类型Review
卷号31期号:2页码:207-219
摘要Schizophrenia is hypothesized to arise from disrupted brain connectivity. This "dysconnectivity hypothesis" has generated interest in discovering whether there is anatomical and functional dysconnectivity between the prefrontal cortex (PFC) and other brain regions, and how this dysconnectivity is linked to the impaired cognitive functions and aberrant behaviors of schizophrenia. Critical advances in neuroimaging technologies, including diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI), make it possible to explore these issues. DTI affords the possibility to explore anatomical connectivity in the human brain in vivo and fMRI can be used to make inferences about functional connections between brain regions. In this review, we present major advances in the understanding of PFC anatomical and functional dysconnectivity and their implications in schizophrenia. We then briefly discuss future prospects that need to be explored in order to move beyond simple mapping of connectivity changes to elucidate the neuronal mechanisms underlying schizophrenia.
关键词prefrontal cortex schizophrenia anatomical connectivity functional connectivity
收录类别SCI
语种英语
WOS记录号WOS:000352152800007
引用统计
被引频次:26[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/13515
专题中国科学院行为科学重点实验室
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China
3.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing 100190, Peoples R China
4.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China
5.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia
6.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Minist Educ, Key Lab NeuroInformat, Chengdu 610054, Peoples R China
推荐引用方式
GB/T 7714
Zhou, Yuan,Fan, Lingzhong,Qiu, Chenxiang,et al. Prefrontal cortex and the dysconnectivity hypothesis of schizophrenia[J]. NEUROSCIENCE BULLETIN,2015,31(2):207-219.
APA Zhou, Yuan,Fan, Lingzhong,Qiu, Chenxiang,&Jiang, Tianzi.(2015).Prefrontal cortex and the dysconnectivity hypothesis of schizophrenia.NEUROSCIENCE BULLETIN,31(2),207-219.
MLA Zhou, Yuan,et al."Prefrontal cortex and the dysconnectivity hypothesis of schizophrenia".NEUROSCIENCE BULLETIN 31.2(2015):207-219.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
WOS_000352152800007.(330KB)期刊论文出版稿暂不开放CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhou, Yuan]的文章
[Fan, Lingzhong]的文章
[Qiu, Chenxiang]的文章
百度学术
百度学术中相似的文章
[Zhou, Yuan]的文章
[Fan, Lingzhong]的文章
[Qiu, Chenxiang]的文章
必应学术
必应学术中相似的文章
[Zhou, Yuan]的文章
[Fan, Lingzhong]的文章
[Qiu, Chenxiang]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。