PSYCH OpenIR  > 中国科学院心理健康重点实验室
Anticipatory pleasure predicts effective connectivity in the mesolimbic system
Liu, Zhi1,2; Yan, Chao3; Xie, Wei-Zhen4; Li, Ke5; Zeng, Ya-Wei5; Jin, Zhen5; Cheung, Eric F. C.6; Chan, Raymond C. K.1
AbstractConvergent evidence suggests the important role of the mesolimbic pathway in anticipating monetary rewards. However, the underlying mechanism of how the sub-regions interact with each other is still not clearly understood. Using dynamic causal modeling, we constructed a reward-related network for anticipating monetary reward using the Monetary Incentive Delay Task. Twenty-six healthy adolescents (Female/Male = 11/15; age = 18.69 +/- 1.35 years; education = 12 +/- 1.58 years) participated in the present study. The best-fit network involved the right substantia nigra/ventral tegmental area (SN/VTA), the right nucleus accumbens (NAcc) and the right thalamus, which were all activated during anticipation of monetary gain and loss. The SN/VTA directly activates the NAcc and the thalamus. More importantly, monetary gain modulated the connectivity from the SN/VTA to the NAcc and this was significantly correlated with subjective anticipatory pleasure (r = 0.649, p < 0.001). Our findings suggest that activity in the mesolimbic pathway during the anticipation of monetary reward could to some extent be predicted by subjective anticipatory pleasure.
Keywordhedonic capacity monetary reward dynamic causal modeling anticipatory pleasure
Indexed BySCI
WOS IDWOS:000359603500001
Citation statistics
Document Type期刊论文
Affiliation1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.E China Normal Univ, Sch Psychol & Cognit Sci, Key Lab Brain Funct Genom MOE & STCSM, Shanghai 200062, Peoples R China
4.Univ Calif Riverside, Dept Psychol, Riverside, CA 92521 USA
5.Hosp 306 PLA, MRI Ctr, Beijing, Peoples R China
6.Castle Peak Hosp, Tuen Mun, Hong Kong, Peoples R China
First Author Affilication认知与发展心理学研究室
Recommended Citation
GB/T 7714
Liu, Zhi,Yan, Chao,Xie, Wei-Zhen,et al. Anticipatory pleasure predicts effective connectivity in the mesolimbic system[J]. FRONTIERS IN BEHAVIORAL NEUROSCIENCE,2015,9(9):217.
APA Liu, Zhi.,Yan, Chao.,Xie, Wei-Zhen.,Li, Ke.,Zeng, Ya-Wei.,...&Chan, Raymond C. K..(2015).Anticipatory pleasure predicts effective connectivity in the mesolimbic system.FRONTIERS IN BEHAVIORAL NEUROSCIENCE,9(9),217.
MLA Liu, Zhi,et al."Anticipatory pleasure predicts effective connectivity in the mesolimbic system".FRONTIERS IN BEHAVIORAL NEUROSCIENCE 9.9(2015):217.
Files in This Item:
File Name/Size DocType Version Access License
WOS_000359603500001.(1287KB)期刊论文出版稿暂不开放CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Liu, Zhi]'s Articles
[Yan, Chao]'s Articles
[Xie, Wei-Zhen]'s Articles
Baidu academic
Similar articles in Baidu academic
[Liu, Zhi]'s Articles
[Yan, Chao]'s Articles
[Xie, Wei-Zhen]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Liu, Zhi]'s Articles
[Yan, Chao]'s Articles
[Xie, Wei-Zhen]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.