Regional homogeneity approach to fMRI data analysis

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	Regional homogeneity approach to fMRI data analysis
	Zang, YF ; Jiang, TZ ; Lu, YL ; He, Y ; Tian, LX
	2004-05-01
发表期刊	NEUROIMAGE
ISSN	1053-8119
文章类型	Article
卷号	22 期号:1 页码:394-400
摘要	Kendall's coefficient concordance (KCC) can measure the similarity of a number of time series. It has been used for purifying a given cluster in functional MRI (fMRI). In the present study, a new method was developed based on the regional homogeneity (ReHo), in which KCC was used to measure the similarity of the time series of a given voxel to those of its nearest neighbors in a voxel-wise way. Six healthy subjects performed left and right finger movement tasks in event-related design five of them were additionally scanned in a rest condition. KCC was compared among the three conditions (left finger movement, right finger movement, and the rest). Results show that bilateral primary motor cortex (M1) had higher KCC in either left or right finger movement condition than in rest condition. Contrary to prediction and to activation pattern, KCC of ipsilateral M1 is significantly higher than contralateral M1 in unilateral finger movement conditions. These results support the previous electrophysiologic findings of increasing ipsilateral M1 excitation during unilateral movement. ReHo can consider as a complementary method to model-driven method, and it could help reveal the complexity of the human brain function. More work is needed to understand the neural mechanism underlying ReHo. (C) 2004 Elsevier Inc. All rights reserved.
关键词	fMRI Kendall's coefficient concordance motor cortex general linear model
收录类别	SCI
语种	英语
WOS记录号	WOS:000221190200041
引用统计
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/13975
专题	中国科学院心理研究所回溯数据库(1956-2010)
作者单位	1.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Key Lab Mental Hlth, Beijing 100101, Peoples R China
推荐引用方式 GB/T 7714	Zang, YF,Jiang, TZ,Lu, YL,et al. Regional homogeneity approach to fMRI data analysis[J]. NEUROIMAGE,2004,22(1):394-400.
APA	Zang, YF,Jiang, TZ,Lu, YL,He, Y,&Tian, LX.(2004).Regional homogeneity approach to fMRI data analysis.NEUROIMAGE,22(1),394-400.
MLA	Zang, YF,et al."Regional homogeneity approach to fMRI data analysis".NEUROIMAGE 22.1(2004):394-400.