PSYCH OpenIR  > 中国科学院心理健康重点实验室
Revisiting the therapeutic effect of rTMS on negative symptoms in schizophrenia: A meta-analysis
Shi, Chuan1,2,3,4; Yu, Xin3,4; Cheung, Eric F. C.5; Shum, David H. K.6; Chan, Raymond C. K.1,2
2014-03-30
发表期刊PSYCHIATRY RESEARCH
ISSN0165-1781
文章类型Review
卷号215期号:3页码:505-513
摘要This study sought to determine the moderators in the treatment effect of repetitive transcranial magnetic stimulation (rTMS) on negative symptoms in schizophrenia. We performed a meta-analysis of prospective studies on the therapeutic application of rTMS in schizophrenia assessing the effects of both low-frequency and high-frequency rTMS on negative symptoms. Results indicate that rTMS is effective in alleviating negative symptoms in schizophrenia. The effect size was moderate (0.63 and 0.53, respectively). The effect size of rTMS on negative symptoms in sham-controlled trials was 0.80 as measured by the SANS and 0.41 as measured by the PANSS. A longer duration of illness was associated with poorer efficacy of rTMS on negative symptoms. A 10 Hz setting, at least 3 consecutive weeks of treatment, treatment site at the left dorsolateral prefrontal cortex (DLPFC) and a 110% motor threshold (MT) were found to be the best rTMS parameters for the treatment of negative symptoms. The results of our meta-analysis suggest that rTMS is an effective treatment option for negative symptoms in schizophrenia. The moderators of rTMS on negative symptoms included duration of illness, stimulus frequency, duration of illness, position and intensity of treatment as well as the type of outcome measures used. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
关键词Negative symptoms Repetitive transcranial magnetic stimulation Schizophrenia Intervention Meta-analysis
收录类别SSCI
语种英语
WOS记录号WOS:000333776500002
引用统计
被引频次:50[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/14133
专题中国科学院心理健康重点实验室
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
4.Peking Univ, Minist Hlth, Key Lab Mental Hlth, Beijing 100871, Peoples R China
5.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
6.Griffith Univ, Griffith Hlth Inst, Behav Basis Hlth Res Program, Gold Coast, Australia
推荐引用方式
GB/T 7714
Shi, Chuan,Yu, Xin,Cheung, Eric F. C.,et al. Revisiting the therapeutic effect of rTMS on negative symptoms in schizophrenia: A meta-analysis[J]. PSYCHIATRY RESEARCH,2014,215(3):505-513.
APA Shi, Chuan,Yu, Xin,Cheung, Eric F. C.,Shum, David H. K.,&Chan, Raymond C. K..(2014).Revisiting the therapeutic effect of rTMS on negative symptoms in schizophrenia: A meta-analysis.PSYCHIATRY RESEARCH,215(3),505-513.
MLA Shi, Chuan,et al."Revisiting the therapeutic effect of rTMS on negative symptoms in schizophrenia: A meta-analysis".PSYCHIATRY RESEARCH 215.3(2014):505-513.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
WOS_000333776500002.(1033KB)期刊论文出版稿暂不开放CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Shi, Chuan]的文章
[Yu, Xin]的文章
[Cheung, Eric F. C.]的文章
百度学术
百度学术中相似的文章
[Shi, Chuan]的文章
[Yu, Xin]的文章
[Cheung, Eric F. C.]的文章
必应学术
必应学术中相似的文章
[Shi, Chuan]的文章
[Yu, Xin]的文章
[Cheung, Eric F. C.]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。