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Genetic and Environmental Etiologies of Adolescent Dysfunctional Attitudes: A Twin Study
Chen, Jie; Li, Xinying
2014-02-01
发表期刊TWIN RESEARCH AND HUMAN GENETICS
ISSN1832-4274
文章类型Article
卷号17期号:1页码:16-22
摘要Despite the importance of dysfunctional attitudes in the development and maintenance of depression, little is known about the etiological origin of dysfunctional attitudes. The Dysfunctional Attitudes Scale for Children was administered to 674 adolescent twins derived from the Beijing Twin Study (BeTwiSt). Four hundred and thirty-nine monozygotic and 235 same-gender dizygotic twin pairs were included. Approximately 54% were females. The age range of the twins was 11-17 years. Model-fitting analyses were conducted. Biometric genetic model-fitting estimates indicated that additive genetic factors accounted for 31% (95% CI: 11%, 45%) of variance in adolescent dysfunctional attitude. The influence of shared environmental factors was small and negligible (9% [95% CI: 0%, 27%]). Non-shared environmental factors explained 60% (95% CI: 55%, 66%) of variance. Equating the estimate parameters across gender or age groups resulted in a non-significant difference of model fit, but there were trends suggesting higher heritability in females and older adolescents. Our results provide evidence for moderate heritability of dysfunctional attitudes in adolescents. Dysfunctional attitudes can be used as an endophenotype to identify risk genes for depression.
关键词dysfunctional attitudes genetic and environmental influences twin study
收录类别SCI
语种英语
WOS记录号WOS:000331900800003
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被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/14152
专题中国科学院心理健康重点实验室
作者单位Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
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Chen, Jie,Li, Xinying. Genetic and Environmental Etiologies of Adolescent Dysfunctional Attitudes: A Twin Study[J]. TWIN RESEARCH AND HUMAN GENETICS,2014,17(1):16-22.
APA Chen, Jie,&Li, Xinying.(2014).Genetic and Environmental Etiologies of Adolescent Dysfunctional Attitudes: A Twin Study.TWIN RESEARCH AND HUMAN GENETICS,17(1),16-22.
MLA Chen, Jie,et al."Genetic and Environmental Etiologies of Adolescent Dysfunctional Attitudes: A Twin Study".TWIN RESEARCH AND HUMAN GENETICS 17.1(2014):16-22.
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