The influence of anhedonia on feedback negativity in major depressive disorder

	The influence of anhedonia on feedback negativity in major depressive disorder
	Liu, Wen-hua 1,2,3; Wang, Ling-zhi 3; Shang, He-rui 1; Shen, Yue 1; Li, Zhi 1; Cheung, Eric F. C.4; Chan, Raymond C. K.2
摘要	Anhedonia is associated with reward-processing deficits of the dopamine system, which may increase the risk of depression. Nevertheless, few previous studies have examined the influence of hedonic tone on event-related potential (ERP) measures of reward processing in major depressive disorder. A simple gambling task was used to elicit feedback negativity (FN), an ERP component elicited by feedback indicating gain versus loss, in 27 patients with major depression and 27 healthy participants. We found that participants with depression were characterized by reduced FN responses, especially towards monetary gains, but not losses, compared with healthy individuals. In addition, the amplitude of FN to gain feedback in participants with depression was related to anhedonia severity and depressive symptoms. These findings indicate an association between low hedonic capacity and reduction in FN. As a neural measure of reward sensitivity, FN may be generated in part by reward-related activity. (C) 2013 Elsevier Ltd. All rights reserved.
关键词	Anhedonia Depression Feedback negativity Reward Event-related potential
	2014
语种	英语
发表期刊	NEUROPSYCHOLOGIA
ISSN	0028-3932
卷号	53 期号:0 页码:213-220
期刊论文类型	Article
收录类别	SSCI
WOS记录号	WOS:000331663100023
引用统计	被引频次：154[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/14229
专题	中国科学院心理健康重点实验室
作者单位	1.Guangzhou Med Univ, Fac Hlth Management, Guangzhou, Guangdong, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China 3.Guangzhou Psychiat Hosp, Guangzhou, Guangdong, Peoples R China 4.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
第一作者单位	认知与发展心理学研究室
推荐引用方式 GB/T 7714	Liu, Wen-hua,Wang, Ling-zhi,Shang, He-rui,et al. The influence of anhedonia on feedback negativity in major depressive disorder[J]. NEUROPSYCHOLOGIA,2014,53(0):213-220.
APA	Liu, Wen-hua.,Wang, Ling-zhi.,Shang, He-rui.,Shen, Yue.,Li, Zhi.,...&Chan, Raymond C. K..(2014).The influence of anhedonia on feedback negativity in major depressive disorder.NEUROPSYCHOLOGIA,53(0),213-220.
MLA	Liu, Wen-hua,et al."The influence of anhedonia on feedback negativity in major depressive disorder".NEUROPSYCHOLOGIA 53.0(2014):213-220.

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