PSYCH OpenIR  > 健康与遗传心理学研究室
低强度半导体激光照射调节成纤维细胞时钟基因表达
Alternative TitleModulation of Low Intensity Laser Irradiation on Expression Suppression of Circadian Clock Genes in Cultured Fibroblasts
朱玲1; 吴德峰1; 王永庆1; 刘承宜1
2011
Source Publication中国激光
Correspondent Emailliutcy@scnu.edu.cn
ISSN0258-7025
Subtype期刊论文
Volume38Issue:8Pages:138-143
Contribution Rank2
Abstract研究了低强度810nm半导体激光(LIDL)对肿瘤坏死因子α(TNF-α)抑制的NIH3T3成纤维细胞时钟基因表达的调节作用。马血清休克2h的细胞用质量浓度为10ng/mL的TNF-α孵育,分别用不同剂量的LIDL照射一次。结果表明LIDL可以调节TNF-α对NIH3T3成纤维细胞时钟基因表达的抑制作用,而且这种调节作用可能是通过烟酰胺腺嘌呤二核苷酸辅酶与其还原形式的比值(NAD+/NADH)和Ⅲ型组蛋白去乙酰化酶1(SIRT1)实现的。
Other AbstractThe effects of low intensity 810 nm laser irradiation (LIDL) to the tumor necrosis factor (TNF)-α induced expression suppression of circadian clock genes in cultured NIH3T3 fibroblasts are investigated. The fibroblasts shocked by horse serum for 2 h are induced with TNF-α of 10 ng/mL, and then irradiated by different doses of LIDL once. The results show that TNF-α induced inhibition effect of the circadian clock gene expression can be modulated by LIDL, which may be mediated by nicotinamide adenine dinucleotide/ reduced form of nicotinamide adenine dinucleotid (NAD+/NADH) and sirtuin 1 (SIRT1).
Keyword生物光学 低强度激光 时钟基因 组蛋白去乙酰化酶
Subject Area生理心理学/生物心理学
URL查看原文
Indexed ByCSCD
Language中文
Funding Organization国家自然科学基金(60878061)资助课题.
CSCD IDCSCD:4282636
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/14497
Collection健康与遗传心理学研究室
Corresponding Author刘承宜
Affiliation1.华南师范大学体育科学学院激光运动医学实验室和民族健康与体质研究中心
2.中国科学院心理研究所
Recommended Citation
GB/T 7714
朱玲,吴德峰,王永庆,等. 低强度半导体激光照射调节成纤维细胞时钟基因表达[J]. 中国激光,2011,38(8):138-143.
APA 朱玲,吴德峰,王永庆,&刘承宜.(2011).低强度半导体激光照射调节成纤维细胞时钟基因表达.中国激光,38(8),138-143.
MLA 朱玲,et al."低强度半导体激光照射调节成纤维细胞时钟基因表达".中国激光 38.8(2011):138-143.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[朱玲]'s Articles
[吴德峰]'s Articles
[王永庆]'s Articles
Baidu academic
Similar articles in Baidu academic
[朱玲]'s Articles
[吴德峰]'s Articles
[王永庆]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[朱玲]'s Articles
[吴德峰]'s Articles
[王永庆]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.