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母婴分离的动物模型及其神经生物学机制
Alternative TitleThe Animal Model and Neurobiological Mechanisms of Maternal Separation
薛晓芳1; 李曼1; 王玮文1; 邵枫1
2013
Source Publication心理科学进展
ISSN1671-3710
Subtype期刊论文
Volume21Issue:6Pages:990-998
Contribution Rank2
Abstract利用社会环境剥夺建立的精神分裂症动物模型,是当前研究精神分裂症神经生物学机制的一个热点课题。作为一种重要的早期社会剥夺方式,出生后至断乳前的母婴分离日益受到关注。文章综合阐述了母婴分离对啮齿类动物行为及神经发育影响的最新研究成果,表明母婴分离可以部分模拟精神分裂症的行为及中枢表现,证实了该模型的可行性;并进一步分析了影响实验结果的各种相关因素,为今后采用该模型进行深入研究提供一定的理论支持。
Other AbstractEstablishment of animal models of schizophrenia through the social environmental deprivation was the focuses for understanding the neurobiological mechanisms underlying this severe mental disease. As an important means of early social environmental deprivation, maternal separation from birth to weaning is being regarding increasingly. By comprehensively describes the latest research results about the impact of maternal separation on rodent behavior and neurodevelopment, this article shows that the feasibility of maternal separation on studying schizophrenia; what's more, further analysis of the various factors which is influencing the results, provides some theoretical support for in-depth study in the future.
Keyword母婴分离 动物模型 精神分裂症
Subject Area生理心理学/生物心理学
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Indexed ByCSCD
Language中文
Funding Organization国家自然科学基金项目资助(批准号31070910).
CSCD IDCSCD:4861691
Citation statistics
Cited Times:2[CSCD]   [CSCD Record]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/14757
Collection中国科学院心理健康重点实验室
Corresponding Author邵枫
Affiliation1.北京大学心理学系
2.中国科学院心理健康重点实验室
3.中国科学院心理研究所
Recommended Citation
GB/T 7714
薛晓芳,李曼,王玮文,等. 母婴分离的动物模型及其神经生物学机制[J]. 心理科学进展,2013,21(6):990-998.
APA 薛晓芳,李曼,王玮文,&邵枫.(2013).母婴分离的动物模型及其神经生物学机制.心理科学进展,21(6),990-998.
MLA 薛晓芳,et al."母婴分离的动物模型及其神经生物学机制".心理科学进展 21.6(2013):990-998.
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