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微生物与行为和精神疾病
Alternative TitleMicroorganism and Behavior and Psychiatric Disorders
梁姗1; 王涛1; 胡旭1; 李薇1; 金锋1; 王沥1
2012
Source Publication心理科学进展
Correspondent Emailjinfeng@psych.ac.cn
ISSN1671-3710
Subtype期刊论文
Volume20Issue:1Pages:75-97
Contribution Rank1
Abstract病原微生物能够影响宿主的大脑和行为,甚至诱发精神疾患。肠道细菌可影响小鼠的神经系统发育和行为模式的发展。慢性胃肠病、慢性疲劳综合征等生理疾病中的行为改变与微生物有关;肝性脑病、多发性硬化等中枢神经系统生理疾病也可能由微生态改变引起;抑郁症、孤独症等精神疾病与肠道细菌状态和比例有关;卫生假说支持上述观点。建立良好的共生微生物平衡有利于人类身心健康。可以预期,共生微生物与身心健康的关系将是今后心理学研究的关注热点。
Other AbstractAs we know that some pathogenic microorganisms not only influence host brain and behaviors, but also cause psychiatric disorders. Recent researches indicate that beneficial symbiotic microorganisms, which also known as probiotics, may improve host health both physically and mentally. Gut microorganisms are involved in the development of the neural system and behavioral pattern of mice. They are also related to chronic gastrointestinal disorders and chronic fatigue syndrome. Some central nervous system diseases, such as hepatic encephalopathy and multiple sclerosis may be induced by the disturbance of gut micro-ecosystems. Depression and autism also may be related to the status and proportion of gut microorganisms. The observations above are consistent with the hygiene hypothesis. Balanced symbiotic microorganisms could play an important role in human physical and mental health. Although the mechanisms still remain to be clarified, various hypotheses and research models will give us a better understanding of the role of gut-brain axis in host health. We believe that the relation of symbiotic microorganisms and host health will become a promising research subject in psychology.
Keyword共生微生物 抑郁 第二大脑 炎症 卫生假说
Subject Area生理心理学/生物心理学
URL查看原文
Indexed ByCSCD
Language中文
Funding Organization日本NSBJ乳酸菌研究特别寄付金.
CSCD IDCSCD:4437454
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Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/14955
Collection健康与遗传心理学研究室
Corresponding Author金锋
Affiliation1.中国科学院心理研究所
2.中国科学院遗传与发育生物学研究所
First Author AffilicationInstitute of Psychology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Psychology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
梁姗,王涛,胡旭,等. 微生物与行为和精神疾病[J]. 心理科学进展,2012,20(1):75-97.
APA 梁姗,王涛,胡旭,李薇,金锋,&王沥.(2012).微生物与行为和精神疾病.心理科学进展,20(1),75-97.
MLA 梁姗,et al."微生物与行为和精神疾病".心理科学进展 20.1(2012):75-97.
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