PSYCH OpenIR  > 应用研究版块
汶川地震幸存者创伤后应激反应与细胞免疫的关系
Alternative TitleRelationship between Posttraumatic Stress Syndrome Severity and Cellular Immunity of "5·12" Wenchuan Earthquake Survivors
彭树增1; 陈纯1; 李凤珍1; 颜小焰1; 周琦1; 王力1; 张雨青1; 吴坎坎1
2012
Source Publication中国健康心理学杂志
Correspondent Emailwukk@psych.ac.cn
ISSN1005-1252
Subtype期刊论文
Volume20Issue:12Pages:1866-1868
Contribution Rank2
Abstract目的探讨自然灾害后创伤后应激反应与细胞免疫之间的关系。方法在汶川地震18个月时通过PTSD症状自评量表(PCL)对205名5.12汶川地震极重灾区教师的创伤后应激反应严重程度的测评和T细胞及其亚群水平的化验和分析。结果通过对102名PCL高分组被试和103名PCL低分组被试的T淋巴细胞及其亚群进行t检验发现,两组被试在CD3水平上存在显著差异(P=0.050),在CD4/CD8水平上存在边缘性显著差异(P=0.069)。进一步的秩和相关分析发现,CD3对创伤后应激反应的4个症状都呈边缘性显著的负相关(闯入、回避、麻木和高警觉的P值分别是0.098、0.081、0.065、0.073),而CD4/CD8仅对PTSD中的高警觉症状呈显著负相关(P<0.05)。结论地震18个月后幸存者的CD3水平可以作为PTSD的生物标记,而CD4:CD8的值则可以作为PTSD的高警觉症状的生物标记。
Other AbstractObjective To explore the relationship between severity of Posttraumatic Stress Syndrome(PTSD)and cellular immunity of natural disaster.Methods The PTSD was measured by PTSD Chicklist(PCL)18-month after "5.12" Wenchuan earthquake,T cell and sub-populations were also tested.Results The percentage of CD3(P=0.050)and the ratio of CD4:CD8(P=0.069)were significant differences between the high group and the low group.And the spearman rank correlation found that CD3 was sensitivity to all the symptoms of PTSD(the P value intrusion,avoidance,numbing and hyperactive were 0.098,0.081,0.065,0.073).On the other hand,the ratio of CD4:CD8 was only sensitivity(P0.05)to hyperarousal symptom.Conclusion Maybe CD3 is the biomarker of PTSD and the each symptom of PTSD,in addition,the ration of CD4:CD8 is the biomarker of hyperarousal symptom.
Keyword5.12汶川地震 创伤后应激反应 PTSD症状自评量表 细胞免疫
Subject Area创伤心理学
URL查看原文
Language中文
Funding Organization中科院抗震救灾应急研究项目中的“灾后应激心理过程以及心理疾病高危人群的筛查和干预”子课题(O8CX112011) ; 中科院心理所发展基金项目“震后心理应激反应的民族差异及其社会心理模式”(O9CX154015) ; 国家自然科学基金青年项目(30900402)
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/14966
Collection应用研究版块
Corresponding Author吴坎坎
Affiliation1.四川省德阳市人民医院
2.中国科学院心理研究所
Recommended Citation
GB/T 7714
彭树增,陈纯,李凤珍,等. 汶川地震幸存者创伤后应激反应与细胞免疫的关系[J]. 中国健康心理学杂志,2012,20(12):1866-1868.
APA 彭树增.,陈纯.,李凤珍.,颜小焰.,周琦.,...&吴坎坎.(2012).汶川地震幸存者创伤后应激反应与细胞免疫的关系.中国健康心理学杂志,20(12),1866-1868.
MLA 彭树增,et al."汶川地震幸存者创伤后应激反应与细胞免疫的关系".中国健康心理学杂志 20.12(2012):1866-1868.
Files in This Item:
File Name/Size DocType Version Access License
汶川地震幸存者创伤后应激反应与细胞免疫的(158KB)期刊论文作者接受稿限制开放CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[彭树增]'s Articles
[陈纯]'s Articles
[李凤珍]'s Articles
Baidu academic
Similar articles in Baidu academic
[彭树增]'s Articles
[陈纯]'s Articles
[李凤珍]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[彭树增]'s Articles
[陈纯]'s Articles
[李凤珍]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 汶川地震幸存者创伤后应激反应与细胞免疫的关系_彭树增[1].pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.