PSYCH OpenIR  > 中国科学院行为科学重点实验室
Toward neurobiological characterization of functional homogeneity in the human cortex: regional variation, morphological association and functional covariance network organization
Jiang, Lili1,2; Xu, Ting1,2; He, Ye1,2,3; Hou, Xiao-Hui1,2,3; Wang, Jinhui4,5; Cao, Xiao-Yan1,2,4,5; Wei, Gao-Xia1,2; Yang, Zhi1,2; He, Yong6,7,8; Zuo, Xi-Nian1,2,8
2015-09-01
发表期刊BRAIN STRUCTURE & FUNCTION
ISSN1863-2653
文章类型Article
卷号220期号:5页码:2485-2507
摘要Local functional homogeneity of the human cortex indicates the boundaries between functionally heterogeneous regions and varies remarkably across the cortical mantle. It is unclear whether these variations have the neurobiological and structural basis. We employed structural and resting-state functional magnetic resonance imaging scans from 482 healthy subjects and computed the vertex-wise regional homogeneity of low-frequency fluctuations (2dReHo) and five measures of cortical morphology. We then used these metrics to examine regional variation, morphological association and functional covariance network of 2dReHo. Within the ventral visual stream, increases of 2dReHo reflect reduced complexity of information processing or functional hierarchies. Along the divisions of the prefrontal cortex and posteromedial cortex, the gradients of 2dReHo revealed the hierarchical organization within the two association areas, respectively. Individual differences in 2dReHo are associated with those of cortical morphology, and their whole-brain inter-regional covariation is organized into a functional covariance network, comprising five hierarchically organized modules with hubs of both primary sensory and high-order association areas. These highly reproducible observations suggest that local functional homogeneity has neurobiological relevance that is likely determined by anatomical, developmental and neurocognitive factors and should serve as a neuroimaging marker to investigate the human brain function.
关键词Functional homogeneity Prefrontal cortex Posteromedial cortex Functional hierarchy Structural morphometry Functional covariance Network
收录类别SCI
语种英语
WOS记录号WOS:000360069200002
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/15237
专题中国科学院行为科学重点实验室
作者单位1.Chinese Acad Sci, Lab Funct Connectome & Dev, Key Lab Behav Sci, Inst Psychol, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Hangzhou Normal Univ, Ctr Cognit & Brain Disorders, Hangzhou 310036, Zhejiang, Peoples R China
5.Hangzhou Normal Univ, Affiliated Hosp, Hangzhou 310036, Zhejiang, Peoples R China
6.Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100087, Peoples R China
7.Beijing Normal Univ, Int Data Grp, McGovern Inst Brain Res, Beijing 100087, Peoples R China
8.Beijing Normal Univ, Ctr Collaborat & Innovat Brain & Learning Sci, Beijing 100087, Peoples R China
推荐引用方式
GB/T 7714
Jiang, Lili,Xu, Ting,He, Ye,et al. Toward neurobiological characterization of functional homogeneity in the human cortex: regional variation, morphological association and functional covariance network organization[J]. BRAIN STRUCTURE & FUNCTION,2015,220(5):2485-2507.
APA Jiang, Lili.,Xu, Ting.,He, Ye.,Hou, Xiao-Hui.,Wang, Jinhui.,...&Zuo, Xi-Nian.(2015).Toward neurobiological characterization of functional homogeneity in the human cortex: regional variation, morphological association and functional covariance network organization.BRAIN STRUCTURE & FUNCTION,220(5),2485-2507.
MLA Jiang, Lili,et al."Toward neurobiological characterization of functional homogeneity in the human cortex: regional variation, morphological association and functional covariance network organization".BRAIN STRUCTURE & FUNCTION 220.5(2015):2485-2507.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
WOS_000360069200002.(3817KB)期刊论文出版稿暂不开放CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Jiang, Lili]的文章
[Xu, Ting]的文章
[He, Ye]的文章
百度学术
百度学术中相似的文章
[Jiang, Lili]的文章
[Xu, Ting]的文章
[He, Ye]的文章
必应学术
必应学术中相似的文章
[Jiang, Lili]的文章
[Xu, Ting]的文章
[He, Ye]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。