Elevated Blood Ammonia Level Is a Potential Biological Risk Factor of Behavioral Disorders in Prisoners

	Elevated Blood Ammonia Level Is a Potential Biological Risk Factor of Behavioral Disorders in Prisoners
	Duan, Yunfeng1 ; Wu, Xiaoli 1,2; Liang, Shan1,2 ; Jin, Feng1
通讯作者邮箱	jinfeng@psych.ac.cn
摘要	Hydrothion (H2S) and ammonia (NH3) can be toxic for the human central nervous system and cause psychological disturbances and behavioral disorders. In order to evaluate the association between the two potential toxicants and mental health, in this study, we compare amale prisoner and control population. Forty-ninemale prisoners and 52 control volunteers took part in the study. An aggressive behavior assessment, the Self-Rating Depression Scale (SDS), and the State-Trait Anxiety Inventory (STAI) were used to characterize the participants' mental health status. Venous blood was collected for detection of H2S andNH(3). The results indicated that blood NH3 was significantly higher in male prisoners than in controls. However, blood H2S was significantly lower. Blood NH3 was also significantly and positively correlated with prisoners. In the multivariate adjusted models, after controlling for age, education, marital status, and BMI, we found a positive association between NH3 and prisoners, but not blood H2S. While the functions of the two toxicants were quite different, blood NH3 may be a potential biological risk factor for behavioral disorders and blood H2S showed neuroprotection. Additionally, the impact of other factors such as diet and gut bacteria should be considered when evaluating risk for behavioral disorders.
	2015
语种	英语
发表期刊	BEHAVIOURAL NEUROLOGY
ISSN	0953-4180
期号	2015 页码:797862
期刊论文类型	Article
收录类别	SCI
WOS记录号	WOS:000362014500001
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/15268
专题	中国科学院心理健康重点实验室
通讯作者	Jin, Feng
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100101, Peoples R China
第一作者单位	中国科学院心理健康重点实验室
通讯作者单位	中国科学院心理健康重点实验室
推荐引用方式 GB/T 7714	Duan, Yunfeng,Wu, Xiaoli,Liang, Shan,et al. Elevated Blood Ammonia Level Is a Potential Biological Risk Factor of Behavioral Disorders in Prisoners[J]. BEHAVIOURAL NEUROLOGY,2015(2015):797862.
APA	Duan, Yunfeng,Wu, Xiaoli,Liang, Shan,&Jin, Feng.(2015).Elevated Blood Ammonia Level Is a Potential Biological Risk Factor of Behavioral Disorders in Prisoners.BEHAVIOURAL NEUROLOGY(2015),797862.
MLA	Duan, Yunfeng,et al."Elevated Blood Ammonia Level Is a Potential Biological Risk Factor of Behavioral Disorders in Prisoners".BEHAVIOURAL NEUROLOGY .2015(2015):797862.

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