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The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells
Li, Lianqin1; Yu, Ai-Qun2,3,4
2015-12-01
发表期刊JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
ISSN0171-5216
文章类型Review
卷号141期号:12页码:2071-2077
摘要The mammalian peroxiredoxin (PRX) family contains six members that provide antioxidant defense in different cell types by removing reactive oxygen species (ROS) through conserved active cysteines. Different from other members, PRX3 is predominantly located in mitochondria, a major apoptosis mediator. The purpose of this review is to summarize the findings on PRX3 concerning its role in ROS removal, apoptosis, and chemoresistance of cancer cells.
关键词Peroxiredoxin (PRX) Reactive oxygen species (ROS) Oxidative stress Apoptosis Cancer
收录类别SCI
语种英语
WOS记录号WOS:000364224800001
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被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/15311
专题健康与遗传心理学研究室
作者单位1.Binzhou Med Univ, Dept Obstet & Gynecol, Yantai Affiliated Hosp, Yantai 264100, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
4.Beijing Technol & Business Univ, Canvard Coll, Beijing 101118, Peoples R China
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Li, Lianqin,Yu, Ai-Qun. The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells[J]. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,2015,141(12):2071-2077.
APA Li, Lianqin,&Yu, Ai-Qun.(2015).The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells.JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,141(12),2071-2077.
MLA Li, Lianqin,et al."The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells".JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 141.12(2015):2071-2077.
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