PSYCH OpenIR  > 中国科学院行为科学重点实验室
Putting age-related task activation into large-scale brain networks: A meta-analysis of 114 fMRI studies on healthy aging
Li, Hui-Jie1,2,3; Hou, Xiao-Hui1,2,3,4; Liu, Han-Hui5; Yue, Chun-Lin6; Lu, Guang-Ming7; Zuo, Xi-Nian1,2,3,8
2015-10-01
发表期刊NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
ISSN0149-7634
文章类型Review
卷号57期号:0页码:156-174
摘要Normal aging is associated with cognitive decline and underlying brain dysfunction. Previous studies concentrated less on brain network changes at a systems level. Our goal was to examine these age-related changes of fMRI-derived activation with a common network parcellation of the human brain function, offering a systems-neuroscience perspective of healthy aging. We conducted a series of meta-analyses on a total of 114 studies that included 2035 older adults and 1845 young adults. Voxels showing significant age-related changes in activation were then overlaid onto seven commonly referenced neuronal networks. Older adults present moderate cognitive decline in behavioral performance during fMRI scanning, and hypo-activate the visual network and hyper-activate both the frontoparietal control and default mode networks. The degree of increased activation in frontoparietal network was associated with behavioral performance in older adults. Age-related changes in activation present different network patterns across cognitive domains. The systems neuroscience approach used here may be useful for elucidating the underlying network mechanisms of various brain plasticity processes during healthy aging. (C) 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
关键词Aging Neural Network Default Mode Cognitive Control Connectomics
收录类别SCI
语种英语
WOS记录号WOS:000364271200011
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/15320
专题中国科学院行为科学重点实验室
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Lab Funct Connectome & Development, Beijing 100101, Peoples R China
4.Shanxi Med Univ, Hosp 1, Dept Psychiat, Taiyuan 030001, Peoples R China
5.China Youth Univ Polit Studies, Youth Work Dept, Beijing 100089, Peoples R China
6.Soochow Univ, Inst Sports Med, Suzhou 215006, Peoples R China
7.Nanjing Univ, Sch Med, Dept Med Imaging, Nanjing 210002, Jiangsu, Peoples R China
8.Southwest Univ, Fac Psychol, Chongqing 400715, Peoples R China
推荐引用方式
GB/T 7714
Li, Hui-Jie,Hou, Xiao-Hui,Liu, Han-Hui,et al. Putting age-related task activation into large-scale brain networks: A meta-analysis of 114 fMRI studies on healthy aging[J]. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,2015,57(0):156-174.
APA Li, Hui-Jie,Hou, Xiao-Hui,Liu, Han-Hui,Yue, Chun-Lin,Lu, Guang-Ming,&Zuo, Xi-Nian.(2015).Putting age-related task activation into large-scale brain networks: A meta-analysis of 114 fMRI studies on healthy aging.NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,57(0),156-174.
MLA Li, Hui-Jie,et al."Putting age-related task activation into large-scale brain networks: A meta-analysis of 114 fMRI studies on healthy aging".NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 57.0(2015):156-174.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Putting age-related (3463KB)期刊论文作者接受稿暂不开放CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Li, Hui-Jie]的文章
[Hou, Xiao-Hui]的文章
[Liu, Han-Hui]的文章
百度学术
百度学术中相似的文章
[Li, Hui-Jie]的文章
[Hou, Xiao-Hui]的文章
[Liu, Han-Hui]的文章
必应学术
必应学术中相似的文章
[Li, Hui-Jie]的文章
[Hou, Xiao-Hui]的文章
[Liu, Han-Hui]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。