Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression

doi:10.1016/j.jad.2015.10.050

	Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression
	Liu, Wen-hua 1,2,3; Roiser, Jonathan P.4; Wang, Ling-zhi 3; Zhu, Yu-hua 3; Huang, Jia2 ; Neumann, David L.5,6; Shum, David H. K.5,6; Cheung, Eric F. C.7; Chan, Raymond C. K.2
摘要	Background: Anhedonia is a cardinal feature of major depression and is hypothesized to be driven by low motivation, in particular blunted reward sensitivity. It has been suggested to be a marker that represents a genetic predisposition to this disorder. However, little is known about the mechanisms underlying this heightened risk in unaffected first-degree relatives of patients with major depression. We previously demonstrated abnormal reward biases in acutely depressed patients. The present study aimed to examine the development of reward bias in first-degree relatives of patients with major depression.
关键词	Depression Reward Anhedonia Risk factors
	2016-01-15
语种	英语
DOI	10.1016/j.jad.2015.10.050
发表期刊	JOURNAL OF AFFECTIVE DISORDERS
ISSN	0165-0327
卷号	190 期号:0 页码:640-648
期刊论文类型	Article
收录类别	SCI ; SSCI
WOS关键词	HAMILTON-PLEASURE SCALE ; HIGH FAMILIAL RISK ; HEDONIC CAPACITY ; DECISION-MAKING ; FEEDBACK NEGATIVITY ; INCENTIVE SALIENCE ; ADULT OUTPATIENTS ; PERCEIVED STRESS ; BIPOLAR DISORDER ; PREDICTION ERROR
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
WOS研究方向	Neurosciences & Neurology ; Psychiatry
WOS类目	Clinical Neurology ; Psychiatry
WOS记录号	WOS:000366463000088
引用统计	被引频次：33[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/15444
专题	中国科学院心理健康重点实验室
作者单位	1.Guangzhou Med Univ, Fac Hlth Management, Guangzhou, Guangdong, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Key Lab Mental Hlth, Beijing 100101, Peoples R China 3.Guangzhou Med Univ, Affiliated Hosp, Guangzhou Psychiat Hosp, Guangzhou, Guangdong, Peoples R China 4.UCL, Inst Cognit Neurosci, London WC1E 6BT, England 5.Menzies Hlth Inst Queensland, Gold Coast, Australia 6.Griffith Univ, Sch Appl Psychol, Gold Coast, Australia 7.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
第一作者单位	认知与发展心理学研究室
推荐引用方式 GB/T 7714	Liu, Wen-hua,Roiser, Jonathan P.,Wang, Ling-zhi,et al. Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression[J]. JOURNAL OF AFFECTIVE DISORDERS,2016,190(0):640-648.
APA	Liu, Wen-hua.,Roiser, Jonathan P..,Wang, Ling-zhi.,Zhu, Yu-hua.,Huang, Jia.,...&Chan, Raymond C. K..(2016).Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression.JOURNAL OF AFFECTIVE DISORDERS,190(0),640-648.
MLA	Liu, Wen-hua,et al."Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression".JOURNAL OF AFFECTIVE DISORDERS 190.0(2016):640-648.

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