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Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression
Liu, Wen-hua1,2,3; Roiser, Jonathan P.4; Wang, Ling-zhi3; Zhu, Yu-hua3; Huang, Jia2; Neumann, David L.5,6; Shum, David H. K.5,6; Cheung, Eric F. C.7; Chan, Raymond C. K.2
2016-01-15
Source PublicationJOURNAL OF AFFECTIVE DISORDERS
ISSN0165-0327
SubtypeArticle
Volume190Issue:0Pages:640-648
AbstractBackground: Anhedonia is a cardinal feature of major depression and is hypothesized to be driven by low motivation, in particular blunted reward sensitivity. It has been suggested to be a marker that represents a genetic predisposition to this disorder. However, little is known about the mechanisms underlying this heightened risk in unaffected first-degree relatives of patients with major depression. We previously demonstrated abnormal reward biases in acutely depressed patients. The present study aimed to examine the development of reward bias in first-degree relatives of patients with major depression.
KeywordDepression Reward Anhedonia Risk factors
DOI10.1016/j.jad.2015.10.050
Indexed BySCI ; SSCI
Language英语
WOS Research AreaNeurosciences & Neurology ; Psychiatry
WOS SubjectClinical Neurology ; Psychiatry
WOS IDWOS:000366463000088
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordHAMILTON-PLEASURE SCALE ; HIGH FAMILIAL RISK ; HEDONIC CAPACITY ; DECISION-MAKING ; FEEDBACK NEGATIVITY ; INCENTIVE SALIENCE ; ADULT OUTPATIENTS ; PERCEIVED STRESS ; BIPOLAR DISORDER ; PREDICTION ERROR
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Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/15444
Collection中国科学院心理健康重点实验室
Affiliation1.Guangzhou Med Univ, Fac Hlth Management, Guangzhou, Guangdong, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Key Lab Mental Hlth, Beijing 100101, Peoples R China
3.Guangzhou Med Univ, Affiliated Hosp, Guangzhou Psychiat Hosp, Guangzhou, Guangdong, Peoples R China
4.UCL, Inst Cognit Neurosci, London WC1E 6BT, England
5.Menzies Hlth Inst Queensland, Gold Coast, Australia
6.Griffith Univ, Sch Appl Psychol, Gold Coast, Australia
7.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
Recommended Citation
GB/T 7714
Liu, Wen-hua,Roiser, Jonathan P.,Wang, Ling-zhi,et al. Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression[J]. JOURNAL OF AFFECTIVE DISORDERS,2016,190(0):640-648.
APA Liu, Wen-hua.,Roiser, Jonathan P..,Wang, Ling-zhi.,Zhu, Yu-hua.,Huang, Jia.,...&Chan, Raymond C. K..(2016).Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression.JOURNAL OF AFFECTIVE DISORDERS,190(0),640-648.
MLA Liu, Wen-hua,et al."Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression".JOURNAL OF AFFECTIVE DISORDERS 190.0(2016):640-648.
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