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Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression
Liu, Wen-hua1,2,3; Roiser, Jonathan P.4; Wang, Ling-zhi3; Zhu, Yu-hua3; Huang, Jia2; Neumann, David L.5,6; Shum, David H. K.5,6; Cheung, Eric F. C.7; Chan, Raymond C. K.2
2016-01-15
发表期刊JOURNAL OF AFFECTIVE DISORDERS
ISSN0165-0327
文章类型Article
卷号190期号:0页码:640-648
摘要Background: Anhedonia is a cardinal feature of major depression and is hypothesized to be driven by low motivation, in particular blunted reward sensitivity. It has been suggested to be a marker that represents a genetic predisposition to this disorder. However, little is known about the mechanisms underlying this heightened risk in unaffected first-degree relatives of patients with major depression. We previously demonstrated abnormal reward biases in acutely depressed patients. The present study aimed to examine the development of reward bias in first-degree relatives of patients with major depression.
关键词Depression Reward Anhedonia Risk factors
DOI10.1016/j.jad.2015.10.050
收录类别SCI ; SSCI
语种英语
WOS研究方向Neurosciences & Neurology ; Psychiatry
WOS类目Clinical Neurology ; Psychiatry
WOS记录号WOS:000366463000088
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]HAMILTON-PLEASURE SCALE ; HIGH FAMILIAL RISK ; HEDONIC CAPACITY ; DECISION-MAKING ; FEEDBACK NEGATIVITY ; INCENTIVE SALIENCE ; ADULT OUTPATIENTS ; PERCEIVED STRESS ; BIPOLAR DISORDER ; PREDICTION ERROR
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被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/15444
专题中国科学院心理健康重点实验室
作者单位1.Guangzhou Med Univ, Fac Hlth Management, Guangzhou, Guangdong, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Key Lab Mental Hlth, Beijing 100101, Peoples R China
3.Guangzhou Med Univ, Affiliated Hosp, Guangzhou Psychiat Hosp, Guangzhou, Guangdong, Peoples R China
4.UCL, Inst Cognit Neurosci, London WC1E 6BT, England
5.Menzies Hlth Inst Queensland, Gold Coast, Australia
6.Griffith Univ, Sch Appl Psychol, Gold Coast, Australia
7.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
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Liu, Wen-hua,Roiser, Jonathan P.,Wang, Ling-zhi,et al. Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression[J]. JOURNAL OF AFFECTIVE DISORDERS,2016,190(0):640-648.
APA Liu, Wen-hua.,Roiser, Jonathan P..,Wang, Ling-zhi.,Zhu, Yu-hua.,Huang, Jia.,...&Chan, Raymond C. K..(2016).Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression.JOURNAL OF AFFECTIVE DISORDERS,190(0),640-648.
MLA Liu, Wen-hua,et al."Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression".JOURNAL OF AFFECTIVE DISORDERS 190.0(2016):640-648.
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