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The Potential Role of Probiotics in Cancer Prevention and Treatment
Yu, Ai-Qun1,2,3; Li, Lianqin4
摘要The human gut microbiota has a significant effect on many aspects of human physiology such as metabolism, nutrient absorption, and immune function. Imbalance of the microbiota has been implicated in many disorders including inflammatory bowel disease, obesity, asthma, psychiatric illnesses, and cancers. As a kind of functional foods, probiotics have been shown to play a protective role against cancer development in animal models. Clinical application of probiotics indicated that some probiotic strains could diminish the incidence of postoperative inflammation in cancer patients. Chemotherapy or radiotherapy-related diarrhea was relieved in patients who were administered oral probiotics. The present review summarizes the up-to-date studies on probiotic effects and the underlying mechanisms related to cancer. At present, it is commonly accepted that most commercial probiotic products are generally safe and can improve the health of the host. By modulating intestinal microbiota and immune response, some strains of probiotics can be used as an adjuvant for cancer prevention or/and treatment.
2016
语种英语
DOI10.1080/01635581.2016.1158300
发表期刊NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
ISSN0163-5581
卷号68期号:4页码:535-544
期刊论文类型Article
收录类别SCI
WOS关键词LACTOBACILLUS-RHAMNOSUS GG ; ABERRANT CRYPT FOCI ; POSTOPERATIVE INFECTIOUS COMPLICATIONS ; RADIATION-INDUCED DIARRHEA ; LACTIC-ACID BACTERIA ; RANDOMIZED CONTROLLED-TRIAL ; COLITIS-ASSOCIATED CANCER ; SPRAGUE-DAWLEY RATS ; HUMAN COLON CELLS ; COLORECTAL-CANCER
WOS标题词Science & Technology ; Life Sciences & Biomedicine
WOS研究方向Oncology ; Nutrition & Dietetics
WOS类目Oncology ; Nutrition & Dietetics
WOS记录号WOS:000378171700001
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被引频次:77[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符https://ir.psych.ac.cn/handle/311026/20023
专题健康与遗传心理学研究室
作者单位1.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
3.Shanghai Lida Polytech Inst, Shanghai, Peoples R China
4.Binzhou Med Univ, Yantai Affiliated Hosp, Dept Obstet & Gynecol, 717 Jinbu St, Yantai 264100, Peoples R China
第一作者单位中国科学院心理研究所
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Yu, Ai-Qun,Li, Lianqin. The Potential Role of Probiotics in Cancer Prevention and Treatment[J]. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL,2016,68(4):535-544.
APA Yu, Ai-Qun,&Li, Lianqin.(2016).The Potential Role of Probiotics in Cancer Prevention and Treatment.NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL,68(4),535-544.
MLA Yu, Ai-Qun,et al."The Potential Role of Probiotics in Cancer Prevention and Treatment".NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL 68.4(2016):535-544.
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