Increased activity in frontal motor cortex compensates impaired speech perception in older adults

doi:10.1038/ncomms12241

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	Increased activity in frontal motor cortex compensates impaired speech perception in older adults
	Du, Yi1,2 ; Buchsbaum, Bradley R.1,3; Grady, Cheryl L.1,3; Alain, Claude 1,3
通讯作者邮箱	duyi@psych.ac.cn
摘要	Understanding speech in noisy environments is challenging, especially for seniors. Although evidence suggests that older adults increasingly recruit prefrontal cortices to offset reduced periphery and central auditory processing, the brain mechanisms underlying such compensation remain elusive. Here we show that relative to young adults, older adults show higher activation of frontal speech motor areas as measured by functional MRI during a syllable identification task at varying signal-to-noise ratios. This increased activity correlates with improved speech discrimination performance in older adults. Multivoxel pattern classification reveals that despite an overall phoneme dedifferentiation, older adults show greater specificity of phoneme representations in frontal articulatory regions than auditory regions. Moreover, older adults with stronger frontal activity have higher phoneme specificity in frontal and auditory regions. Thus, preserved phoneme specificity and upregulation of activity in speech motor regions provide a means of compensation in older adults for decoding impoverished speech representations in adverse listening conditions.
学科领域	老年心理学
	2016-08-01
语种	英语
DOI	10.1038/ncomms12241
发表期刊	Nature Communications
ISSN	2041-1723
卷号	7 期号:0 页码:1-12
期刊论文类型	Article
收录类别	SCI
WOS关键词	AGE-RELATED-CHANGES ; AUDITORY-CORTEX ; NOISE ; RECOGNITION ; REPRESENTATIONS ; ORGANIZATION ; MEMORY ; DEDIFFERENTIATION ; CONNECTIVITY ; PERFORMANCE
WOS标题词	Science & Technology
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000380855800001
资助机构	Canadian Institutes of Health Research(MOP106619)
引用统计	被引频次：123[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/20332
专题	认知与发展心理学研究室
通讯作者	Du, Yi; Alain, Claude
作者单位	1.Baycrest Ctr Geriatr Care, Rotman Res Inst, Toronto, ON M6A 2E1, Canada 2.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China 3.Univ Toronto, Dept Psychol, Toronto, ON M8V 2S4, Canada
第一作者单位	中国科学院心理研究所
通讯作者单位	中国科学院心理研究所
推荐引用方式 GB/T 7714	Du, Yi,Buchsbaum, Bradley R.,Grady, Cheryl L.,et al. Increased activity in frontal motor cortex compensates impaired speech perception in older adults[J]. Nature Communications,2016,7(0):1-12.
APA	Du, Yi,Buchsbaum, Bradley R.,Grady, Cheryl L.,&Alain, Claude.(2016).Increased activity in frontal motor cortex compensates impaired speech perception in older adults.Nature Communications,7(0),1-12.
MLA	Du, Yi,et al."Increased activity in frontal motor cortex compensates impaired speech perception in older adults".Nature Communications 7.0(2016):1-12.

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