Anodal Stimulation of the Left DLPFC Increases IGT Scores and Decreases Delay Discounting Rate in Healthy Males

doi:10.3389/fpsyg.2016.01421

	Anodal Stimulation of the Left DLPFC Increases IGT Scores and Decreases Delay Discounting Rate in Healthy Males
	He, Qinghua 1,2,3,4; Chen, Mei 1,2; Chen, Chuansheng 5; Xue, Gui 6; Feng, Tingyong 1,2; Bechara, Antoine 7,8
通讯作者邮箱	heqinghua@swu.edu.cn
摘要	Previous correlational imaging studies have implicated the dorsolateral prefrontal cortex (DLPFC) in decision making. Using High-Definition Transcranial Direct Current Stimulation (HD-tDCS), the present study directly investigated the causal role of the DLPFC in performing the Iowa Gambling Task (IGT) and the Inter-Temporal Choice (ITC) task. Three experiments were conducted: Experiment 1 (N = 41) to study the left DLPFC, Experiment 2 (N = 49) to study the right DLPFC, and Experiment 3 (N = 20, a subset of those in Experiment 1) to switch the experimental and control conditions. All participants were healthy male college students. For Experiments 1 and 2, participants were randomly assigned to either the HD-tDCS or the sham stimulation condition. For Experiment 3, participants were assigned to the condition they were not in during Experiment 1. Results showed that HD-tDCS over the left DLPFC increased IGT score, decreased the recency parameter in IGT, and lowered delay discounting rate (k) in the ITC task. We discussed the potential roles of impulse control and time perception in mediating the effect of tDCS stimulation of left DLPFC on decision making. Our results have clinical implications for the treatment of disorders involving poor decision-making, such as addictions.
关键词	Decision Making Hd-tdcs Dlpfc Igt Inter-temporal Choice Task
	2016-09-20
语种	英语
DOI	10.3389/fpsyg.2016.01421
发表期刊	FRONTIERS IN PSYCHOLOGY
ISSN	1664-1078
卷号	7 期号:0 页码:1-4
期刊论文类型	Article
收录类别	SSCI
WOS关键词	DORSOLATERAL PREFRONTAL CORTEX ; IOWA GAMBLING TASK ; PERCEPTUAL DECISION-MAKING ; INFERIOR FRONTAL-CORTEX ; INTERTEMPORAL CHOICE ; IMPULSE CONTROL ; SEX-DIFFERENCES ; SELF-CONTROL ; INDIVIDUAL-DIFFERENCES ; BRAIN ACTIVATION
WOS标题词	Social Sciences
WOS研究方向	Psychology
WOS类目	Psychology, Multidisciplinary
WOS记录号	WOS:000383441600002
资助机构	National Natural Science Foundation of China(31400959) ; Open Research Fund of the National Key Laboratory of Cognitive Neuroscience and Learning(CNLZD1306) ; Fundamental Research Funds for the Central Universities(SWU1509422 ; Open Research Fund of the Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences(KLMH2015G01) ; Research Program Funds of the Collaborative innovation Center of Assessment toward Basic Education Quality at Beijing Normal University(2016-06-014-BZK01) ; 15XDSKD004)
引用统计	被引频次：45[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.psych.ac.cn/handle/311026/20468
专题	中国科学院心理健康重点实验室
通讯作者	He, Qinghua
作者单位	1.Southwest Univ, Fac Psychol, Decis Neurosci Lab, Chongqing, Peoples R China 2.Southwest Univ, Minist Educ, Key Lab Cognit & Personal, Chongqing, Peoples R China 3.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing, Peoples R China 4.Beijing Normal Univ, Collaborat Innovat Ctr Assessment Basic Educ Qual, Southwest Univ Branch, Chongqing, Peoples R China 5.Univ Calif Irvine, Dept Psychol & Social Behav, Irvine, CA 92697 USA 6.Beijing Normal Univ, IDG McGovern Inst Brain Res, Natl Key Lab Cognit Neurosci & Learning, Beijing, Peoples R China 7.Univ So Calif, Brain & Creat Inst, Los Angeles, CA 90089 USA 8.Univ So Calif, Dept Psychol, Los Angeles, CA 90089 USA
第一作者单位	中国科学院心理健康重点实验室
通讯作者单位	中国科学院心理健康重点实验室
推荐引用方式 GB/T 7714	He, Qinghua,Chen, Mei,Chen, Chuansheng,et al. Anodal Stimulation of the Left DLPFC Increases IGT Scores and Decreases Delay Discounting Rate in Healthy Males[J]. FRONTIERS IN PSYCHOLOGY,2016,7(0):1-4.
APA	He, Qinghua,Chen, Mei,Chen, Chuansheng,Xue, Gui,Feng, Tingyong,&Bechara, Antoine.(2016).Anodal Stimulation of the Left DLPFC Increases IGT Scores and Decreases Delay Discounting Rate in Healthy Males.FRONTIERS IN PSYCHOLOGY,7(0),1-4.
MLA	He, Qinghua,et al."Anodal Stimulation of the Left DLPFC Increases IGT Scores and Decreases Delay Discounting Rate in Healthy Males".FRONTIERS IN PSYCHOLOGY 7.0(2016):1-4.

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