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Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence
Randesi, Matthew1; van den Brink, Wim2,3; Levran, Orna1; Blanken, Peter2,4; Butelman, Eduardo R.1; Yuferov, Vadim1; da Rosa, Joel Correa7; Ott, Jurg5,6; van Ree, Jan M.2,8; Kreek, Mary Jeanne1
2016-11-01
发表期刊DRUG AND ALCOHOL DEPENDENCE
ISSN0376-8716
文章类型Article
卷号168期号:0页码:164-169
摘要

Background: Heroin addiction is a chronic, relapsing brain disease. Genetic factors are involved in the development of drug addiction. The aim of this study was to determine whether specific variants in genes of the opioid system are associated with non-dependent opioid use and heroin dependence.

关键词Heroin Addiction Non-dependent Opioid Use Heroin-assisted Treatment Opioid Genes Rs2236861
DOI10.1016/j.drugalcdep.2016.08.634
收录类别SCI ; SSCI
语种英语
项目资助者Dr. Miriam and Sheldon G. Adelson Medical Research Foundation ; NIDA(P50-DA005130) ; Natural Science Foundation of China(31470070) ; Netherlands Ministry of Health, Welfare and Sports ; (R01-DA012848)
WOS研究方向Substance Abuse ; Psychiatry
WOS类目Substance Abuse ; Psychiatry
WOS记录号WOS:000387523800023
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]CENTRAL SWEDEN ; DRUG-ABUSE ; ADDICTION ; RECEPTOR ; POPULATION ; GENETICS ; COCAINE ; BRAIN ; POLYMORPHISMS ; VULNERABILITY
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/20766
专题健康与遗传心理学研究室
作者单位1.Rockefeller Univ, Lab Biol Addict Dis, 1230 York Ave,Box 171, New York, NY 10065 USA
2.Cent Comm Treatment Heroin Addicts CCBH, Utrecht, Netherlands
3.Univ Amsterdam, Acad Med Ctr, Dept Psychiat, Amsterdam Inst Addict Res, POB 22660, NL-1100 DD Amsterdam, Netherlands
4.PARC, Brijder Addict Treatment, POB 53002, NL-2505 AA The Hague, Netherlands
5.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China
6.Rockefeller Univ, Lab Stat Genet, 1230 York Ave, New York, NY 10065 USA
7.Rockefeller Univ, Ctr Clin & Translat Sci, 1230 York Ave, New York, NY 10065 USA
8.Univ Utrecht, Univ Med Ctr Utrecht, Brain Ctr Rudolf Magnus, NL-3508 TC Utrecht, Netherlands
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Randesi, Matthew,van den Brink, Wim,Levran, Orna,et al. Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence[J]. DRUG AND ALCOHOL DEPENDENCE,2016,168(0):164-169.
APA Randesi, Matthew.,van den Brink, Wim.,Levran, Orna.,Blanken, Peter.,Butelman, Eduardo R..,...&Kreek, Mary Jeanne.(2016).Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence.DRUG AND ALCOHOL DEPENDENCE,168(0),164-169.
MLA Randesi, Matthew,et al."Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence".DRUG AND ALCOHOL DEPENDENCE 168.0(2016):164-169.
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