|其他题名||The specialization of cross-modality tactile face processing in the blind: an fMRI study|
|Rui Dai; Zirui Huang; Xuchu Weng; Sheng He|
|其他摘要||PURPOSE: Previous studies demonstrated that fusiform face area (FFA) is the core region of face processing, which is largely innate and tuned by visual experience. However, the degree to which the face-selectivity of FFA was genetic determined remains unclear. Moreover, evidence is still lacking on elucidating the neural plasticity of the FFA in other sensory modalities (e.g. tactile).|
METHODS: To investigate these questions, we studied 38 eyesight obstacle disabled subjects, who consist of four sub-groups: congenital blind, early blind, late blind and low vision. All subjects were trained ~3 hrs on perceiving man-made tactile faces and other complex object categories. Functional magnetic resonance imaging (fMRI) was performed both before and after training.
RESULTS: We found robust face-selective activation in the FFA in both the early blind and low vision subjects after training. In contrast, this was not seen in the congenital blind or late blind subjects.
CONCLUSIONS: Our results suggest that even after more than 14 years of absence of visual face exposure, the FFA can still quickly become engaged in processing face information, and even from a different sensory modality. However, despite of strong genetic determined, the specialization of face processing requires an initial visual driven start.
|关键词||fusiform face area visual experience cross-modal plasticity the blind tactile training|
|作者单位||1.Center for Cognition and Brain Disorders, Hangzhou Normal University, 58 Haishu Road, Cangqian Dist., Hangzhou, China, 311121|
2.School of Life Science, South China Normal University, 55 Zhongshan Road, Tianhe Dist., Guangzhou, China, 510631
3.Institute of Mental Health Research, University of Ottawa, Ottawa, ON, Canada, K1Z 7K4
4.State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang Dist., Beijing, China, 100101
5.Department of Psychology, University of Minnesota, Minneapolis, MN, United States of America, 55414
|Rui Dai,Zirui Huang,Xuchu Weng,等. 关于盲人的跨通道触觉面孔选择性的功能性磁共振研究[C]. 见:2016年第一届北京视觉科学会议. 北京. 2016-07.http://vision.csp.escience.cn/dct/page/1.|