初级视皮层方位信息处理过程中不同抑制系统受老化的影响不同——周边抑制增强但局部抑制系统减弱或保持
Alternative TitleAging increases lateral but not local inhibition of orientation processing in primary visual cortex
Zhengchun Wang; Shan Yu; Yu Fu
2016
Conference Name2016年第一届北京视觉科学会议
Conference Date2016-07
Conference Place北京
Funding Organization中国科学院心理研究所
Other Abstract

PURPOSE: Aging-related declines in vision can decrease well-being of the elder. Concerning early sensory changes as in the primary visual cortex, physiological and behavioral reports seem contradictory. Neurophysiological studies on orientation tuning properties suggested that neuronal changes might come from decreased cortical local inhibition. However, behavioral results either showed no clear deficits in orientation processing in the elder, or proposed stronger surround suppression. We try to resolve these discrepancies by combining psychophysical, modeling and neurophysiological data re-analysis techniques.
METHODS: The current study firstly used psychophysical experiments to probe the age-related inhibition systems changes refected by behavioral performance. Secondly, a computational modeling was applied to identify the detail parameters changes underlying these age-related phenomenon. Finally, we also re-analyzing published neurophysiological data of senescence macaque, which confirmed our behavioral and modeling findings.
RESULTS: We resolved these discrepancies by demonstrating stronger lateral inhibition in the elder while neuronal orientation tuning widths, related to local inhibition, stayed globally intact across age. We confirmed this finding by re-analyzing published neurophysiological data that showed no systematic tuning width changes, but instead a higher neuronal noise with aging.   
CONCLUSIONS: These results suggest a stronger lateral inhibition and mixed effects on local inhibition during aging, revealing a more complex picture of age-related effects in the central visual system than previously thought.

Keywordlateral inhibition local inhibition aging orientation processing
Subject Area感知觉心理学
URL查看原文
Indexed By其他
Language英语
Document Type会议论文
Identifierhttp://ir.psych.ac.cn/handle/311026/20822
Collection心理所主办、承办、协办学术会议_2016年第一届北京视觉科学会议_会议摘要
Affiliation1.Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, 230027, China
2.Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, and CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Beijing 100190
3.Medical Faculty, Kunming University of Science and Technology, #727 South Jingming Road, Kunming, Yunnan 650550, China
Recommended Citation
GB/T 7714
Zhengchun Wang,Shan Yu,Yu Fu. 初级视皮层方位信息处理过程中不同抑制系统受老化的影响不同——周边抑制增强但局部抑制系统减弱或保持[C]. 见:2016年第一届北京视觉科学会议. 北京. 2016-07.http://vision.csp.escience.cn/dct/page/1.
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