斜视性弱视患者对运动显著性感知的受损及弱视眼同侧FEF脑区与视觉注意网络的失联
Alternative TitleImpaired motion salience and disconnection of ipsilateral FEF from the attention network in strabismic amblyopia
Hao Wang; Sheila Crewther; Minglong Liang; Robin Laycock; Tao Yu; Bonnie Alexander; David Crewther; Jian Wang; Zhengqin Yin
2016
Conference Name2016年第一届北京视觉科学会议
Conference Date2016-07
Conference Place北京
Funding Organization中国科学院心理研究所
Other Abstract

Purpose: To compare psychophysical performance and brain activation during a motion salience task and voluntary saccadesin adult strabismicamblyopes and controls.
Methods: The motion salience task involved discrimination and detection of a target of coherently moving dots. The second task required voluntary saccades to horizontal stimulus position changes. fMRI activation and functional connectivity between parieto-frontal attention network ROIs, and V1 and V5 were compared for the two tasks.
Results: Behavioural thresholds were higher for detection ofthe moving stimuli by the strabismic amblyopic eye compared to the fellow eye or control eyes. BOLD activation in IPS, FEF and V5 for both tasks, through the amblyopic eye was weaker than that to fellow eye or control subject eyes though no di?erence was seen in V1 activation to the motion task under any eye-viewing condition. Correlational connections between key nodes of the visual attention network activated by the amblyopic eye were abnormal in the motion task, with the FEF ipsilateral to the amblyopic eye the most isolated node.By contrast, the functional connections of this network were relatively normal for the voluntary saccade task.
Conclusions: Amblyopic eyes require slower speed and longer exposure for the detection of moving targets.Overall our results suggest that strabismic amblyopia is associated with reduced attention network activation during motion-driven attention tasks independent of V1.

KeywordStrabismic amblyopia Visual attention fMRI Psychophysics
Subject Area感知觉心理学
URL查看原文
Indexed By其他
Language英语
Document Type会议论文
Identifierhttp://ir.psych.ac.cn/handle/311026/20865
Collection心理所主办、承办、协办学术会议_2016年第一届北京视觉科学会议_会议摘要
Affiliation1.Southwest Eye Hospital/Southwest Hospital, Key Laboratory of Visual Damage and Regeneration and Restoration of Chongqing, Third Military Medical University, Chongqing 400038, China
2.School of Psychological Science, Faculty of Science, Technology and Engineering, La Trobe University, Melbourne, VIC 3086, Australia
3.Department of Radiology, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China.
4.Centre for Human Psychophysiology, Swinburne University of Technology, VIC 3122, Australia.
Recommended Citation
GB/T 7714
Hao Wang,Sheila Crewther,Minglong Liang,等. 斜视性弱视患者对运动显著性感知的受损及弱视眼同侧FEF脑区与视觉注意网络的失联[C]. 见:2016年第一届北京视觉科学会议. 北京. 2016-07.http://vision.csp.escience.cn/dct/page/1.
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