|其他题名||The cortical magnification factor and spatial frequency selectivity in Macaque V1 revealed quantitatively by Intrinsic Optical Imaging|
|Yiliang Lu; Hongliang Gong; Jiapeng Yin; Zheyuan Chen; Ian M. Andolina; Wei Wang|
|其他摘要||PURPOSE: The primary visual cortex (V1) in primates performs a fine spatial analysis of the visual world, with the highest visual acuity in the cortical area corresponding to the fovea of the retina. Electrophysiological single-unit recordings have revealed an inverse proportionality between the receptive ?eld size, spatial frequency (SF) selectivity of V1 neurons and their eccentricities. As eccentricity is measured as the distance (degrees) from the fovea whereas cortical magnification factor (CMF) is calculated as cortical surface distance/visual angle (mm/degree), the correlation between the neural SF selectivity and CMF in macaque V1 has not yet been quantitatively de?ned.|
METHODS: In this study by using intrinsic optical imaging, the SF selectivity of each pixel of the imaged area was measured in response to sinewave gratings with various combinations of orientation and SF. We quantitatively measured the relationship between CMF and SF selectivity, eccentricity as well as orientation domain size in macaque V1.
RESULTS: The ?ne cortical representation of the visual space was mapped and analyzed by using fast Fourier intrinsic optical imaging before the acquisition of the eccentricity and CMF maps with high spatial resolution. A physiometric function for SF selectivity and CMF was thus determined in the imaged areas of macaque V1. We also quantitatively measured the inverse proportionality between eccentricity and CMF and between the size of orientation domains and CMF.
CONCLUSIONS: These quantitative measurements of relationship among SF selectivity, eccentricity, orientation domains and CMF will be highly informative for future electrophysiological recording, other brain imaging studies and computational modeling in primates.
|关键词||Cortical magnification factor Spatial vision Non-human primate|
|作者单位||1.Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Xuhui Dist., Shanghai, China, 200031|
2.University of Chinese Academy of Sciences, 320 Yueyang Road, Xuhui Dist., Shanghai, China, 200031
|Yiliang Lu,Hongliang Gong,Jiapeng Yin,等. 非人灵长类猕猴V1区视皮层放大因子与空间频率选择性相关性的研究[C]. 见:2016年第一届北京视觉科学会议. 北京. 2016-07.|