PSYCH OpenIR  > 中国科学院心理健康重点实验室
Anxiety alters brain activity of response inhibition: evidence from event related potentials and source current density analysis
Yang, Li1; Li, Xue-Bing2; lixb@psych.ac.cn
2014
Conference NameFourth IEEE International Conference on Information Science and Technology
Conference DateApril 26, 2014 - April 28, 2014
Conference PlaceShenzhen, China
Abstract

Anxiety is usually associated with dysfunction of cognitive control. The aim of the present study is to examine whether high anxious individuals have a damage of cognitive control function in a standard response inhibition task, Go/Nogo-paradigm, and to investigate its neural correlates with event-related potentials (ERPs). We focused on the N2 and P3 components in the difference wave between NoGo condition and Go condition, which is considered to reflect different processing stage of response inhibition. The P3 component was mainly influenced by trait anxiety, showing the reduction in HTA group. Using the standardised Low Resolution Electromagnetic Tomography method (sLORETA), we found that the reduced P3 of difference wave in HTA group was associated with the medial frontal gyrus and superior frontal gyrus. Therefore, the attenuation of response inhibition in anxiety is likely mediated by the decreased activation of frontal area.

KeywordTrait anxiety Go/NoGo Event-related potentials Current density analysis
Subject Area健康心理学
Indexed ByEI
Language英语
Document Type会议论文
Identifierhttp://ir.psych.ac.cn/handle/311026/20899
Collection中国科学院心理健康重点实验室
Corresponding Authorlixb@psych.ac.cn
Affiliation1.Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences& University of Chinese Academy of Sciences & Department of Health, Beijing Military General Hospital, Beijing, China
2.Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China
Recommended Citation
GB/T 7714
Yang, Li,Li, Xue-Bing,lixb@psych.ac.cn. Anxiety alters brain activity of response inhibition: evidence from event related potentials and source current density analysis[C],2014.
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