PSYCH OpenIR  > 健康与遗传心理学研究室
非人灵长类的光遗传学研究进展
Alternative TitleThe Progress of Optogenetic Studies in Nonhuman Primates
戴辑; 张弢
First Author戴辑
2016
Source Publication生物化学与生物物理进展
Correspondent Emaildaij@psych.ac.cn
ISSN1000-3282
Subtype期刊论文
Volume43Issue:4Pages:354-360
Contribution Rank1
Abstract

光遗传学是近十年来神经科学领域最受关注的一种神经调控技术.本文首先简要介绍了光遗传技术的工作原理,归纳了该技术在神经调控上的优势,并列出了一些可能的应用方向.随后指出,将光遗传技术与非人灵长类结合是推动该技术转化到临床治疗等领域的必要环节.本文系统回顾了光遗传技术在非人灵长类动物上取得的研究进展,并重点介绍了Dai等的工作.在总结这些工作的基础上,还分析了光遗传技术应用到灵长类研究所面临的一些挑战.最后,本文对筹划中的"中国脑计划"提出一些关于光遗传技术,尤其是在非人灵长类的立项建议.

Other Abstract

In the past decade, optogenetics is one of the most popular neuromodulation techniques in neuroscience. This review first briefly introduces the basic principle of optogenetics and summarizes its advantages in comparing with those traditional methods, and then lists some potential applications of this novel technique. In order to promote the conversion of optogenetie treatment in clinics, it is necessary to integrateoptogenetics with nonhuman primate study. This review then systematically looksback the progress of optogenetic studies in the nonhuman primates, and particularly highlights the work done by Dai et al.. In addition, this review also points out some challenges towards the development of optogenetics in the future. In the end, to advance the optogenetic-related studies, especially in the nonhuman primates, this review proposes some suggestions to the planning "Chinese Brain Initiative" .

Keyword光遗传学 非人灵长类 神经调控 脑功能
Subject Area遗传心理学
DOI10.16476/j.pibb.2016.0113
URL查看原文
Indexed ByCSCD
Language中文
Funding Organization中国科学院心理研究所科研启动经费资助项目(Y5CX112005)
CSCD IDCSCD:5692085
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/21026
Collection健康与遗传心理学研究室
Corresponding Author戴辑
Affiliation脑与认知科学国家重点实验室,中国科学院心理研究所
Recommended Citation
GB/T 7714
戴辑,张弢. 非人灵长类的光遗传学研究进展[J]. 生物化学与生物物理进展,2016,43(4):354-360.
APA 戴辑,&张弢.(2016).非人灵长类的光遗传学研究进展.生物化学与生物物理进展,43(4),354-360.
MLA 戴辑,et al."非人灵长类的光遗传学研究进展".生物化学与生物物理进展 43.4(2016):354-360.
Files in This Item:
File Name/Size DocType Version Access License
非人灵长类的光遗传学研究进展_戴辑.pd(516KB)期刊论文出版稿限制开放CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[戴辑]'s Articles
[张弢]'s Articles
Baidu academic
Similar articles in Baidu academic
[戴辑]'s Articles
[张弢]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[戴辑]'s Articles
[张弢]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 非人灵长类的光遗传学研究进展_戴辑.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.